論文リスト(1991年以降，生殖生物学研究室Sperm Groupのメンバーが主著者の論文のみを抜粋)
【著書・総説・原著論文】
[2011-]
Noda T., O. Shidara and H. Harayama H. Detection of the activator cAMP responsive element modulator (CREM) isoform ortholog proteins in porcine spermatids and sperm. Theriogenology, 77(7): 1360-1368, 2012.
[2006-2010]
Harayama H., K. Nishijima, T. Murase, M. Sakase and M. Fukushima. Relationship of protein tyrosine phosphorylation state with tolerance to frozen storage and the potential to undergo cyclic AMP-dependent hyperactivation in the spermatozoa of Japanese Black bulls. Mol. Reprod. Dev., 77(10): 910-921, 2010.
Tate S., K. Nakamura, C. Suzuki, T. Noda, J. Lee and H. Harayama. Evidence of the existence of adenylyl cyclase 10 (ADCY10) ortholog proteins in the heads and connecting pieces of boar spermatozoa. J. Reprod. Dev., 56(2): 271-278, 2010.
Goto, N. and H. Harayama. Calyculin A-sensitive protein phosphatases are involved in maintenance of progressive movement in mouse spermatozoa in vitro by suppression of autophosphorylation of protein kinase A. J Reprod Dev., 55(3): 55(3):327-334, 2009.
Tabuchi, T., O. Shidara and H. Harayama. A 32-kDa tyrosine-phosphorylated protein shows a protease-dependent increase in dead boar spermatozoa. J Reprod Dev., 54(6): 502-507, 2008.
Harayama, H. and K. Nakamura. Changes of PKA and PDK1 in the principal piece of boar spermatozoa treated with a cell-permeable cAMP analog to induce flagellar hyperactivation. Mol. Reprod. Dev., 75(9):1396-1407, 2008.
Adachi, J., S. Tate, M. Miyake and H. Harayama. Effects of protein phosphatase inhibitor calyculin a on the postacrosomal protein serine/threonine phosphorylation state and acrosome reaction in boar spermatozoa incubated with a cAMP analog. J Reprod Dev., 54(3):171-176, 2008.
Kuroda, K., M. Fukushima and H. Harayama. Premature capacitation of frozen-thawed spermatozoa from subfertile Japanese Black cattle. J. Reprod. Dev., 53, 1079-1086, 2007.
Amano, R., J. Lee, N. Goto and H. Harayama. Evidence for existence of cAMP-Epac signaling in the heads of mouse epididymal spermatozoa. J. Reprod. Dev., 53(1): 127-133, 2007.
Harayama, H. and M. Miyake. A cyclic adenosine 3',5'-monophosphate-dependent protein kinase C activation is involved in the hyperactivation of boar spermatozoa. Mol. Reprod. Dev., 73(9): 1169-1178, 2006.
[2001-2005]
Harayama, H., T., Murase, and M. Miyake. A cyclic adenosine 3',5'-monophosphate stimulates a phospholipase Cgamma1-calcium signaling via the activation of tyrosine kinase in boar spermatozoa. J. Androl., 26(6): 732-740, 2005.
Harayama, H., M. Muroga, and M. Miyake. A cyclic adenosine 3',5'- monophosphate-induced tyrosine phosphorylation of Syk protein tyrosine kinase in the flagella of boar spermatozoa. Mol. Reprod. Dev., 69(4): 436-447, 2004.
Harayama, H., K. Sasaki, and M. Miyake. A unique mechanism for cyclic adenosine 3',5'-monophosphate-induced increase of 32-kDa tyrosine- phosphorylated protein in boar spermatozoa. Mol. Reprod. Dev., 69(2): 194-204, 2004.
Harayama, H. Viability and protein phosphorylation patterns of boar spermatozoa agglutinated by treatment with a cell-permeable cyclic adenosine 3',5'-monophosphate analog. J. Androl. 24(6): 831-842, 2003.
Harayama, H., K. Okada and M. Miyake. Involvement of cytoplasmic free calcium in boar sperm: head-to-head agglutination induced by a cell-permeable cyclic adenosine monophosphate analog. J. Androl. 24(1): 91-99, 2003.
Harayama, H., M. Kaneto, M. Miyake and S. Kato. Capacitation-related events in boar spermatozoa. In Animal Frontier Sciences. Hokuto Shobo, Kyoto, Japan, Sato, E., Miyamoto, H. and Manabe, N. eds. pp. 37-43, 2003.
西本 尚美，中村 弘毅，岩木 史之，岡 章生，福島 護之，太田垣 進，原山 洋. 黒毛和種精漿酸性タンパク質の濃度に及ぼす季節の影響. 日本胚移植学雑誌. 25(2): 101-107, 2003.
Kaneto, M., H. Harayama, M. Miyake and S. Kato. Capacitation-like alterations in cooled boar spermatozoa: assessment by the chlortetracycline staining assay and immunodetection of tyrosine-phosphorylated sperm proteins. Anim. Reprod. Sci. 73(3,4): 197-209, 2002.
Harayama, H. and S. Kato. Relationship between bicarbonate and cyclic nucleotide in the promoting effects on head-to-head agglutination in boar spermatozoa. Asian J. Androl. 4(2): 87-96, 2002.
古塚 正幸，原山 洋，三宅 正史，福島 護之，太田垣 進，加藤 征史郎. 黒毛和種精漿における繁殖能力関連タンパク質Osteopontinの検出. 日本胚移植学雑誌. 24(1): 1-8, 2002.
Harayama, H. and S. Kato. Factors regulating changes of head-to-head agglutinability in boar spermatozoa during epididymal transit and capacitation in vitro -review-. Asian-Aust. J. Anim. Sci. 14(8):1196-1202, 2001.
Harayama, H., T. Murate, M. Miyake and S. Kato. Regulation of head-to-head agglutination in boar spermatozoa by capacitation-related factors. In Reproductive Biotechnology: Reproductive biotechnology update and its related physiology. Hokuto Shobo, Kyoto, Japan, Miyamoto, H. and Manabe, N. eds. pp.203-209, 2001.
[1996-2000]
原山 洋 (2000): 哺乳類精子の成熟変化を制御する分子. J. Reprod. Dev. 46(Suppl., 邦文論文掲載号):J43-J50, 2000.
Harayama, H., M. Miyake and S. Kato. Role of cyclic adenosine 3',5'-monophosphate and serum albumin in head-to-head agglutination of boar spermatozoa. Reprod. Fertil. Dev. 12(5,6):307-318, 2000.
Harayama, H., P.-C. Liao, D.A. Gage, M. Miyake, S. Kato and R.H. Hammerstedt. Biochemical characterization of sialoprotein "anti-agglutinin" purified from boar epididymal and seminal plasma. Mol. Reprod. Dev. 55(1):96-103, 2000.
Harayama, H., S.F. Magargee, E. Kunze, O. Shidara, E. Iwamoto, S. Arikawa, M. Miyake, S. Kato and R.H. Hammerstedt. Changes in epididymal protein anti-agglutinin on ejaculated boar spermatozoa during capacitation in vitro. Reprod. Fertil. Dev. 11(4-5):193-199, 1999.
Harayama, H., M. Miyake and S. Kato. Immunolocalization of anti-agglutinin for spermatozoa in boars. Mol. Reprod. Dev. 52(3):269-276, 1999.
Harayama, H., M. Miyake, O. Shidara, E. Iwamoto and S. Kato. Effects of calcium and bicarbonate on head-to-head agglutination in ejaculated boar spermatozoa. Reprod. Fertil. Dev. 10(5):445-450, 1998.
Harayama, H., S. Watanabe, H. Masuda, Y., Kannan, M. Miyake and S. Kato. Lectin-binding characteristics of extracts from epididymal boar spermatozoa. J. Reprod. Dev. 44(1):21-27, 1998.
Harayama, H., A. Imano and S. Kato. Effects of seminal plasma components on motility and acrosomal integrity of Meishan boar spermatozoa after cooling treatments. Anim. Sci. Technol. (Jpn) 69(8):720-727, 1998.
Harayama, H., T. Miyano, M. Miyake and S. Kato. Purification and characterization of boar epididymal plasma protein Anti-Agglutinin. In Reproductive Biology Update: Novel tools for assessment of environmental toxicity. Nakanishi Pub. Co., Kyoto, Japan, Miyamoto, H. and Manabe, N. eds. pp. 207-217, 1998.
Harayama, H., S. Kato and R.H. Hammerstedt. Electrophoretic characterization of boar epididymal antiagglutinin. Biol. Reprod. 55(2):325-332, 1996.
Harayama, H., T. Shibukawa, M. Miyake, Y. Kannan and S. Kato. Fructose stimulates shedding of cytoplasmic droplets from epididymal boar spermatozoa. Reprod. Fertil. Dev. 8(7):1039-1043, 1996.
Kato, S., T. Shibukawa, H. Harayama and Y. Kannan. Timing of shedding and disintegration of cytoplasmic droplets from boar and goat spermatozoa. J. Reprod. Dev. 42(4):237-241, 1996.
[1991-1995]
Harayama, H., T. Miyano, H. Masuda, M. Miyake and S. Kato. Detection of 25-kDa Anti-Agglutinin in epididymal plasma and spermatozoa collected from various regions of boar epididymis. J. Reprod. Dev. 41(2):113-121, 1995.
Harayama, H., T. Miyano, M. Miyake, H. Kusunoki and S. Kato. Identification of anti-agglutinin for spermatozoa in epididymal boar plasma. Mol. Reprod. Dev. 37(4):436-445, 1994.
Harayama H, H. Kusunoki and S. Kato. Capacity of rete testicular and cauda epididymal boar spermatozoa to undergo the acrosome reaction and subsequent fusion with egg plasma membrane. Mol. Reprod. Dev. 35(1):62-68, 1993.
Harayama, H., H. Kusunoki and S. Kato. Capacity of goat epididymal spermatozoa to undergo the acrosome reaction and subsequent fusion with the egg plasma membrane. Reprod. Fertil. Dev. 5(3):239-246, 1993.
Harayama, H., H. Kusunoki and S. Kato. Motility and penetrability into zona-free hamster eggs of boar spermatozoa collected from various regions of the epididymis. J. Reprod. Dev. 39(1):41-45, 1993.
Harayama, H. and S. Kato. Characteristics of the ejaculates from Meishan boars at various ages. Anim. Reprod. Technol. 64(4):333-339, 1993.
Kato, S., K. Kano, H. Harayama, H. Kusunoki and I. Nanjo. In vitro storage of Meishan boar spermatozoa. Proceedings of the International Symposium on Chinese Pig Breeds. pp. 582-585, 1992.
Harayama, H., M. Miyake and S. Kato. Seasonal changes of reproductive performance in Meishan boars. Proceedings of the International Symposium on Chinese Pig Breeds. pp. 162-165, 1992.
Harayama, H., I. Nanjo, S. Kanda and S. Kato. Development of the epididymis in Meishan boars. Asian-Aust. J. Anim. Sci., 5(1):165-171, 1992.
Harayama, H. and S. Kato. Changes in motility and morphology of spermatozoa during their transit through the epididymis in Meishan boars at various ages. Anim. Sci. Technol. 63(5): 462-467, 1992.
Harayama, H., S. Kanda and S. Kato. Influence of season on characteristics of epididymal and ejaculated semen in Meishan boars. Theriogenology 38(3):491-500, 1992.
Harayama, H. S. Kanda and S. Kato. Development of the accessory genital glands in Meishan boars. Anim. Sci. Technol. 63(11):1115-1122, 1992.
原山 洋，筒井昭夫，加藤 征史郎. 雄金華豚における生殖器. 日本養豚学会誌. 29(3): 174-183, 1992.
Harayama, H., I. Nanjo, S. Kanda and S. Kato. Testicular development in Chinese Meishan boars. Theriogenology 36(4): 637-643, 1991.
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