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HIV/AIDS
We perform basic studies on human immunodeficiency virus type 1 (HIV-1),
the major causative agent of acquired immunodeficiency syndrome (AIDS),
in order to accumulate an information to develop HIV vaccines and novel
anti-HIV compounds. In addition, we attempt to reveal the virological and
immunological characteristics of the Southeast Asian strains of HIV-1,
as well as perform sero- and molecular epidemiological studies to reveal
the HIV-1 prevalence rate and the genotypic characteristics of currently
circulating viral strains in Southeast Asia. These research projects are
conducted in a collaboration with an oversea research collaboration center
of Kobe University established in Indonesia. Through such collaborative
research projects, we aim to accumulate an information which may contribute
to the implementation of HIV/AIDS countermeasures in Sotheast Asia.
Dengue
We perform basic studies on dengue viruses type 1-4, which are causative
agents of dengue and severe dengue, in order to reveal the detailed replication
mechanism as well as to develop novel antiviral compounds, vaccines and
rapid diagnistic methods. In addition, we perform a molecular epidemiological
study to monitor currently circulating viral strains in a collaboration
with the Indonesian research collaboration center of Kobe University.
COVID-19
We started basic researches on the new coronavirus (SARS-CoV-2), such as
the establishment of a coronavirus replicon system, analysis of viral replication
mechanism, measurement of neutralization activity of vaccine candidates,
evaluation of viral inactivation methods, etc.
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