KOBEUNIVERSITY, FACULTY OF AGRICULTURE

Laboratoryof Reproductive Biology and Biotechnology

Last Update Mar 4 2008


 研究室ゼミのご案内 (2007年度)


   生殖生物・発生工学研究室ゼミの日程  場所:自然科学研究棟1号館701

  

   4/10(Tue.)        研究概要説明 

     三宅正史 先生

     宮野隆 先生

      原山洋 先生

  

   4/17(Tue.)        文献紹介(神戸大学農学部 1530

    Thaler CD, Thomas M, Ramalie JR.
Reorganization of mouse sperm lipid rafts by capacitation.
Mol Reprod Dev. 2006 Dec;73(12):1541-9./後藤 名美子

    Duncan FE, Moss SB, Williams CJ.
Knockdown of the cAMP-dependent protein kinase (PKA) Type Ialpha regulatory subunit in mouse oocytes disrupts meiotic arrest and results in meiotic spindle defects.
Dev Dyn. 2006 Nov;235(11):2961-8./ Ilse Cayo

   4/24(Tue.)        文献紹介(神戸大学農学部 1530

    Mery L, Lefevre A, Benchaib M, Demirci B, Salle B, Guerin JF, Lornage J.
Follicular growth in vitro: detection of growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15) during in vitro culture of ovine cortical slices.
Mol Reprod Dev. 2007 Jun;74(6):767-74./竹鶴 祐亮

    Hashimoto S, Ohsumi K, Tsuji Y, Harauma N, Miyata Y, Fukuda A, Hosoi Y, Iritani A, Morimoto Y.
Growing Porcine Oocyte-Granulosa Cell Complexes Acquired Meiotic Competence during In Vitro Culture.
J Reprod Dev. 2006 Dec 20;/ Phan Thuy Chau

   4/27(Fri.)         M1卒論発表(神戸大学農学部 1030

    實川 真弓「RNA合成阻害剤による発育途上ブタ卵母細胞の核小体の形態変化」

    善行 舞「RNA干渉法を用いたマウス卵成熟におけるCry1の機能解析」

    中村 和美 「ブタ精子のキャパシテーションおよび先体反応に及ぼすEpac特異的cAMPアナログ8-pMeOPT-2’-O-Me-cAMPの影響」

    早川 晃平「ラット顆粒層細胞におけるEGF-like factorの発現機構とその役割に関する研究」

    米澤 潤一「マウス初期胚におけるper2cry1の過剰発現が発生に及ぼす影響」

   5/ 1(Tue.)         文献紹介(神戸大学農学部 1530

    Baker MA, Hetherington L, Aitken RJ.
Identification of SRC as a key PKA-stimulated tyrosine kinase involved in the capacitation-associated hyperactivation of murine spermatozoa.
J Cell Sci. 2006 Aug 1;119(Pt 15):3182-92. Epub 2006 Jul 11./西島 和弘

    Hu YC, Wang PH, Yeh S, Wang RS, Xie C, Xu Q, Zhou X, Chao HT, Tsai MY, Chang C.
Subfertility and defective folliculogenesis in female mice lacking androgen receptor.
Proc Natl Acad Sci U S A. 2004 Aug 3;101(31):11209-14. Epub 2004 Jul 26
./ Sumith Magamage

   5/ 8(Tue.)         文献紹介(神戸大学農学部 1530

    Richards JS, Sharma SC, Falender AE, Lo YH.
Expression of FKHR, FKHRL1, and AFX genes in the rodent ovary: evidence for regulation by IGF-I, estrogen, and the gonadotropins.
Mol Endocrinol. 2002 Mar;16(3):580-99. /柏木 弥生

    Kren R, Fulka J, Fulka H.
Cryopreservation of isolated mouse germinal vesicles.
J Reprod Dev. 2005 Apr;51(2):289-92. Epub 2004 Dec 15./
實川 真弓

   5/ 15(Tue.)       文献紹介(神戸大学農学部 1530

    Kinukawa M, Oda S, Shirakura Y, Okabe M, Ohmuro J, Baba SA, Nagata M, Aoki F.
Roles of cAMP in regulating microtubule sliding and flagellar bending in demembranated hamster spermatozoa.
FEBS Lett. 2006 Feb 20;580(5):1515-20. Epub 2006 Feb 2./中村 和美

    Su YQ, Wu X, O'Brien MJ, Pendola FL, Denegre JN, Matzuk MM, Eppig JJ.
Synergistic roles of BMP15 and GDF9 in the development and function of the oocyte-cumulus cell complex in mice: genetic evidence for an oocyte-granulosa cell regulatory loop.
Dev Biol. 2004 Dec 1;276(1):64-73./善行 舞

   5/22(Tue.)        文献紹介(神戸大学農学部 1530

    Polanski Z, Hoffmann S, Tsurumi C..
Oocyte nucleus controls progression through meiotic maturation.
Dev Biol. 2005 May 15;281(2):184-95./正寿 慎太郎

    Hutt KJ, McLaughlin EA, Holland MK.
Primordial follicle activation and follicular development in the juvenile rabbit ovary.
Cell Tissue Res. 2006 Dec;326(3):809-22. Epub 2006 Jul 8./早川 晃平

    Turksen K, Troy TC.
Barriers built on claudins.
J Cell Sci. 2004 May 15;117(Pt 12):2435-47. Review. Erratum in: J Cell Sci. 2004 Aug 15;117(Pt 18):4341.
/米澤 潤一

   5/29 (Tue.)        27CDB合同セミナー(神戸大学遺伝子実験センター5階研究室)

    Effects of Liquid Preservation on The Ability of spermatozoa for Oocyte Activation and Preimplantation Development of Eggs
Nguyen Thanh Bihn(Kobe University)

    Live-cell imaging system of the preimplantation embryo and its application
Kazuo Yamagata(Laoratory for Genome Reprogramming,RIKEN CDB)

   6/19(Tue.)        文献紹介(神戸大学農学部 1530〜)

    Swain JE, Ding J, Brautigan DL, Villa-Moruzzi E, Smith GD.
Proper chromatin condensation and maintenance of histone H3 phosphorylation during mouse oocyte meiosis requires protein phosphatase activity.
Biol Reprod. 2007 Apr;76(4):628-38. Epub 2006 Dec 20. /岡崎 永里子

    Xie F, Garcia MA, Carlson AE, Schuh SM, Babcock DF, Jaiswal BS, Gossen JA, Esposito G, van Duin M, Conti M.
Soluble adenylyl cyclase (sAC) is indispensable for sperm function and fertilization.
Dev Biol. 2006 Aug 15;296(2):353-62. Epub 2006 Jun 7./鈴木 千尋

    Castrillon DH, Miao L, Kollipara R, Horner JW, DePinho RA.
Suppression of ovarian follicle activation in mice by the transcription factor Foxo3a.
Science. 2003 Jul 11;301(5630):215-8./平嶋 友美子

   6/26 (Tue.)        文献紹介(神戸大学農学部 1530〜)

    Hutt DM, Baltz JM, Ngsee JK.
Synaptotagmin VI and VIII and syntaxin 2 are essential for the mouse sperm acrosome reaction.
J Biol Chem. 2005 May 27;280(21):20197-203. Epub 2005 Mar 17./中村 和美

    Shinozawa T, Sugawara A, Matsumoto A, Han YJ, Tomioka I, Inai K, Sasada H, Kobayashi E, Matsumoto H, Sato E.
Development of rat tetraploid and chimeric embryos aggregated with diploid cells.
Zygote. 2006 Nov;14(4):287-97./十河 竜也

   7 / 3 (Tue.)        文献紹介(神戸大学農学部 1530〜)

    Fulka J Jr, Moor RM, Loi P, Fulka J.
Enucleolation of porcine oocytes.
Theriogenology. 2003 Apr 15;59(8):1879-85./ 川 真弓

    Rajareddy S, Reddy P, Du C, Liu L, Jagarlamudi K, Tang W, Shen Y, Berthet C, Peng SL, Kaldis P, Liu K.
p27kip1 (Cdkn1b) controls ovarian development by suppressing follicle endowment and activation, and promoting follicle atresia in mice.
Mol Endocrinol. 2007 Jun 12./善行 舞

   7/10(Tue.)        文献紹介(神戸大学農学部 1530〜)

    Nilsson EE, Detzel C, Skinner MK.
Platelet-derived growth factor modulates the primordial to primary follicle transition.
Reproduction. 2006 Jun;131(6):1007-15./早川 晃平

    Li L, Li S, Cao Z, Peng Z, Han Z.
[Gene expression of insulin-like growth factors in human villous trophoblast cells of early pregnancy in vitro]
Hua Xi Yi Ke Da Xue Xue Bao. 2002 Apr;33(2):186-8. Chinese./
米澤 潤一

   7/17 (Tue.)        28CDB合同セミナー理化学研究所発生・再生科学総合研究センターC棟6階セミナー室)

    To study the role of citrullination in reprogramming and development of early preimplantation embryos
Manjula Brahmajosyula
Kobe University)

    The correlation between transcriptional activity and development of cloned embryo in mice
Bui HT
Laoratory for Genome Reprogramming,RIKEN CDB)

   7/24 (Tue.)        修論中間報告神戸大学農学部 1530〜)

    Ilse S. Cayo

    Phan Thuy Chau

    竹鶴 裕亮

    西島 和弘

   7/27 (Tue.)        修論中間報告(神戸大学農学部 1530〜)

    Sumith Magamage

    柏木 弥生

    後藤 名美子

    正寿 慎太郎

    十河 竜也

   10/2(Tue.)        文献紹介(神戸大学農学部 1530〜)

    Cunningham MA, Zhu Q, Hammond JM.
FoxO1a can alter cell cycle progression by regulating the nuclear localization of p27kip in granulosa cells.
Mol Endocrinol. 2004 Jul;18(7):1756-67. Epub 2004 Apr 15. /柏木 弥生

    Chakrabarti R, Cheng L, Puri P, Soler D, Vijayaraghavan S.
Protein phosphatase PP1 gamma 2 in sperm morphogenesis and epididymal initiation of sperm motility.
Asian J Androl. 2007 Jul;9(4):445-52. Review./後藤 名美子

   10/9 (Tue.)        29CDB合同セミナー(理化学研究所発生・再生科学総合研究センターC棟6階セミナー室)

    The current paradigm of mammalian oocyte cryopreservation, and a proposed alternative.
Steven F. Mullen, Ph. D.
The Comparative Medicine center and Department of Veterinary Pathobiology, University of Missouri-Columbia)

    Developmental ability of individual 2-cell blastomeres in mice.
Mika Katayama, Ph. D.
Division of Animal Science, University of Missouri-Columbia)

   10/23(Tue.)      文献紹介(神戸大学農学部 1510〜)

    Beltran C, Vacquier VD, Moy G, Chen Y, Buck J, Levin LR, Darszon A.
Particulate and soluble adenylyl cyclases participate in the sperm acrosome reaction.
Biochem Biophys Res Commun. 2007 Jul 13;358(4):1128-35. Epub 2007 May 21. /鈴木 千尋

    Ding X, Xu R, Yu J, Xu T, Zhuang Y, Han M.
SUN1 is required for telomere attachment to nuclear envelope and gametogenesis in mice.
Dev Cell. 2007 Jun;12(6):863-72.  /岡崎 永里子

    John GB, Shirley LJ, Gallardo TD, Castrillon DH.
Specificity of the requirement for Foxo3 in primordial follicle activation.
Reproduction. 2007 May;133(5):855-63.  /平嶋 友美子

   11/6(Tue.)        文献紹介(神戸大学農学部 1510〜)

    Marquez B, Suarez SS.
Bovine sperm hyperactivation is promoted by alkaline-stimulated Ca2+ influx.
Biol Reprod. 2007 Apr;76(4):660-5. Epub 2006 Dec 20. /西島 和弘

    Hardy K, Handyside AH.
Metabolism and cell allocation during parthenogenetic preimplantation mouse development.
Mol Reprod Dev. 1996 Mar;43(3):313-22. /十河 竜也

   11/13(Tue.)      文献紹介(神戸大学農学部 1510〜)

    Brenkman AB, Burgering BM
FoxO3a eggs on fertility and aging.
Trends Mol Med.2003 Nov;9(11):4647./
善行 舞

   11/16(Fri .)       卒論中間報告(神戸大学農学部 1530〜)

    平嶋 友美子

    岡崎 永里子

    鈴木 千尋

   11/20(Tue.)      文献紹介(神戸大学農学部 1510〜)

 

    Hikey TE, Marrocco DL, Amato F, Ritter LJ, Norman RJ, Gilchrist RB, Armstrong DT.
Androgens augment the mitogenic effects of oocyte-secreted factors and growth differentiation factor 9 on porcine granulosa cells.
Biol Reprod. 2005 Oct;73(4):825-32. Epub 2005 Jun 22. / Sumith Magamage

 

    Ebeling S, Schuon C, Meinecke B.
Mitogen-activated protein kinase phosphorylation patterns in pig oocytes and cumulus cells during gonadotrophin-induced resumption of meiosis in vitro.

Zygote. 2007 May;15(2):139-47. No abstract available. / Ilse Cayo

 

   11/27(Tue.)      文献紹介(神戸大学農学部 1510〜)

 

    Huo LJ, Fan HY, Liang CG, Yu LZ, Zhong ZS, Chen DY, Sun QY

            Regulation of ubiquitin-proteasome pathway on pig oocyte meiotic maturation and fertilization.

            Biol Reprod. 2004 Sep;71(3):853-62. Epub 2004 Apr 28. /川 真弓

 

           Ohashi S, Sakashita G, Ban R, Nagasawa M, Matsuzaki H, Murata Y, Taniguchi H, Shima H, Furukawa K, Urano T

            Phospho-regulation of human protein kinase Aurora-A: analysis using anti-phospho-Thr288 monoclonal antibodies.

            Oncogene. 2006 Dec 14;25(59):7691-702. Epub 2006 Jun 19. /正寿 慎太郎

 

    Kim DH, Park HS, Kim SW, Hwang IS, Yang BC, Im GS, Chung HJ, Seong HW, Moon SJ, Yang BS

            Vitrification of immature bovine oocytes by the microdrop method.

            J Reprod Dev. 2007 Aug;53(4):843-51. Epub 2007 Apr 26. /竹鶴 裕亮

 

   12/4(Tue.)        文献紹介(神戸大学農学部 1510

    Grasa P, Cebrian-Perez JA, Muino-Blanco T.
Signal transduction mechanisms involved in in vitro ram sperm capacitation.
Reproduction. 2006 Nov;132(5):721-32.
/中村 和美

    Furuse M, Hata M, Furuse K, Yoshida Y, Haratake A, Sugitani Y, Noda T, Kubo A, Tsukita S.
Claudin-based tight junctions are crucial for the mammalian epidermal barrier: a lesson from claudin-1-deficient mice.
J Cell Biol. 2002 Mar 18;156(6):1099-111. Epub 2002 Mar 11.
/米澤 潤一

   12/11(Tue.)      修論英語発表会+文献紹介(神戸大学農学部 1510〜)

    Sumith Magamage

    十河 竜也

    後藤 名美子

    Brahamajosyula Manjula

    Nguyen Thanh Bihn

   12/18(Tue.)      修論英語発表会(神戸大学農学部 1510〜)

    柏木 弥生

    西島 和弘

    Ilse S. Cayo

    正寿 慎太郎

    竹鶴 裕亮

   1/8(Tue.)          文献紹介(神戸大学農学部 1510〜)

    Gallardo TD, John GB, Bradshaw K, Welt C, Reijo-Pera R, Vogt PH, Touraine P, Bione S, Toniolo D, Nelson LM, Zinn AR, Castrillon DH.
Sequence variation at the human FOXO3 locus: a study of premature ovarian failure and primary amenorrhea.
Hum Reprod. 2008 Jan;23(1):216-21. Epub 2007 Oct 23.
 /早川 晃平

   1/15(Tue.)        文献紹介(神戸大学農学部 1510〜)

    Ward EC, Hoekstra AV, Blok LJ, Hanifi-Moghaddam P, Lurain JR, Singh DK, Buttin BM, Schink JC, Kim JJ.
The regulation and function of the forkhead transcription factor, FOXO1, is dependent on the progesterone receptor in endometrial carcinoma.
Endocrinology. 2007 Dec 20; [Epub ahead of print] /
早川 晃平

   1/ 22(Tue.)       文献紹介(神戸大学農学部 1510

 

    Peters AH, OCarroll D, Scherthan H, Mechtler K, Sauer S, Schofer C, Weipoltshammer K, Paganni M, Lachner M, Kohlmaier A, Opravil S, Doyle M, Sibilia M, Jenuwein T.
Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability.

            Cell. 2001 Nov 2;107(3):323-37. /岡崎 永里子

 

           Carlson AE, Hille B, Babcock DF.

            External Ca2+ acts upstream of adenylyl cyclase SACY in the bicarbonate signaled activation of sperm motility.

            Dev Biol. 2007 Dec 1;312(1):183-92. Epub 2007 Sep 20. /鈴木 千尋

 

           Nakayama K, Ishida N, Shirane M, Inomata A, Inoue T, Shishido N, Horii I, Loh DY, Nakayama K.

            Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors.

            Cell. 1996 May 31;85(5):707-20. /平嶋 友美子

  

   2/6 (Tue.)         30回CDB合同セミナー 研究環重点研究チーム 学術講演会神戸大学遺伝子実験センター5階研究室

    The conserved mechanism of protection of centromeric attachment in mammalian mitosis and meiosis.
李 智博(理化学研究所 平野染色体ダイナミクス研究室)

   2/19(Tue.)        B4卒論発表(神戸大学農学部 1510

    平嶋 友美子「マウス卵子形成過程におけるp27Kip1の発現」

    岡崎 永里子「ウシ受精卵におけるヒストン修飾とその後の発生能力」

    鈴木 千尋「ブタ精子における可溶性アデニル酸シクラーゼの検出」

  2/21(Thurs.)      修士論文発表会 (農学部 B401教室 10:20〜)

    後藤 名美子「マウス精子のプロテインフォスファターゼによるcAMPシグナリング抑制機構の解明」

    西島 和弘「ウシ精子のハイパーアクチベーションを制御するcAMP依存性タンパク質チロシンリン酸化反応の解析」

    柏木 弥生 「Foxo3aによるマウス卵母細胞の発育開始制御」

    Magamage M.P. Sumith Effect of steroidal hormones and stem cell factor on the development of pig primordial follicles in vitro

    竹鶴 裕亮 「ガラス化したウシ二次卵胞の体外発育培養」

    Phan Thuy Chau Acquisition of meiotic competence of pig oocytes after growth culture

    Cayo Colka Ilse S. 「Change in protein kinase A (PKA) activity of pig oocytes during in vitro maturation

    正寿 慎太郎 「ブタ卵母細胞に顕微注入された精子核の形態変化とヒストン修飾」

    十河 竜也 「単為発生倍体と受精卵由来倍体キメラにおける単為発生由来細胞の配置と発生能力」

   2/ 26(Tue.)       文献紹介(神戸大学農学部 1510

 

    Rathbone CR, Booth FW, Lees SJ.

FoxO3a preferentially induces p27Kip1 expression while impairing muscle precursor cell-cycle progression.
Muscle Nerve. 2008 Jan;37(1):84-9.
/善行 舞

 

           Moffit JS, Boekelheide K, Sedivy JM, Klysik J.

Mice lacking Raf kinase inhibitor protein-1 (RKIP-1) have altered sperm capacitation and reduced reproduction rates with a normal response to testicular injury.
J Androl. 2007 Nov-Dec;28(6):883-90. Epub 2007 Jun 6.
/中村 和美

 

           Moriwaki K, Tsukita S, Furuse M.

               Tight junctions containing claudin 4 and 6 are essential for blastocyst formation in preimplantation mouse embryos.

               Dev Biol. 2007 Dec 15;312(2):509-22. Epub 2007 Oct 4. /米澤 潤一