Dept. Biofunc. Chem., Kobe
Univ.
1-1 Rokkodai, Nada, Kobe 657-8501
Japan
phone: +81 78 803 5862
fax: +81 78 803
5815
e-mail: kenyoshi@kobe-u.ac.jp
portable phone: +81 90
4279 6263
HONOUR: Awarded a prize for
"Encouragement of Young Scientists" from the Japan Society for Bioscience,
Biotechnology, and Agrochemistry (2002).
HONOUR: Program Officer,
Scientific Research Senior Specialist, Research Promotion Bureau, Ministry of
Education, Culture, Sports, Science and Technology (MEXT), Japan (August
2005).
Name: Ken-ichi Yoshida
Position: Associate professor
Affiliation: Department of Biofunctional Chemistry, Faculty of Agriculture, Kobe University, 1-1 Rokkodai-cho, Nada-ku, Kobe-shi, Hyogo-ken 657-8501 Japan.
Place of birth: Kamigyo-ku, Kyoto, Japan.
Date of birth: 3rd July, 1964.
Education:
Entered Hyogo Prefectural Takarazuka Senior High School, April, 1980, and graduated March, 1983.
Entered Faculty of Agriculture, Kyoto University, April, 1983, and graduated March, 1987, with degree of Bachelor of Agriculture.
Obtained an M.S. ("Nougaku Shushi", literal translation is Master of Agriculture) March, 1989.
Received a Ph.D. ("Hakase (Nougaku)", literal translation is Doctor of Agriculture) November, 1993 from Kyoto University for a thesis entitled: "Analysis of active regions of insecticidal proteins of Bacillusthuringiensis var. israelensis".
Membership:
The Japan Society for Bioscience, Biotechnology, and Agrochemistry; the Molecular Biology Society of Japan; American Society for Microbiology.
Assistant professor--Department of Biotechnology, Faculty of Engineering, Fukuyama University. Bacillus subtilis genome sequencing project, to obtain a large genomic sequence of 177 kb region from the gnt to sacXY loci. Analysis of regulation of the gnt operon for gluconate catabolism of Bacillus subtilis. Analysis of gene organization and regulation of the iol operon for inositol catabolism of Bacillus subtilis. (April, 1990 to March, 1996; April, 1997 to March, 1999).
Postdoctoral research fellow--INRA, Génétique Microbienne (directed by Dr. S. D. Ehrlich), Domaine de Vilvert, 78352 Jouy-en-Josas cedex, France. Bacillus subtilis genome functional analysis project. Establishment and application of the techniques for targeted gene inactivation and transcription analysis. (April, 1996 to March, 1997).
Associate professor (Lecturer)--Department of Biotechnology, Faculty of Engineering, Fukuyama University. Bacillus subtilis genome functional analysis project. Analysis of the three asparagine synthetase genes predicted within the Bacillus subtilis genome after the whole genome sequencing. Transcriptome analysis of Bacillus subtilis using the DNA microarray-chip technology. Analysis of a putative ABC transporter of Bacillus subtilis involved in acetoin assimilation. (April, 1999 to March, 2002).
Associate professor (from April, 2003)--Department of Biotechnology, Faculty of Lifescience and Biotechnology, Fukuyama University. Bacillus subtilis genome functional analysis project. Analysis of the three asparagine synthetase genes predicted within the Bacillus subtilis genome after the whole genome sequencing. Transcriptome analysis of Bacillus subtilis using the DNA microarray-chip technology. Analysis of a putative ABC transporter of Bacillus subtilis involved in acetoin assimilation. (April, 2002 to March 2004).
Associate professor (from April, 2004 to date)--Department of Biofunctional Chemistry, Faculty of Agriculture, Kobe University. Inositol catabolism in Bacillus subtilis 168 and Sinorhizobium fredii USDA191. Analysis of the three asparagine synthetase genes predicted within the Bacillus subtilis genome after the whole genome sequencing. Reverse genetics of drug resistance genes in Bacillus subtilis genome. Induction of nodulation genes of Sinorhizobium fredii USDA191 provoked by flavonoids released from soybeans. Regulation mechanism in activation of aryl hydrocarbon receptor (dioxin receptor) in Hepa 1c1c cells. Translocation of GLUT4 for glucose uptake in 3T3-L1 adipose cells and L1 muscle cells provoked by polyphenols.
Assistant professor--Department of Biotechnology, Faculty of Engineering, Fukuyama University. Three technical courses for undergraduate students; Basic techniques for biotechnology, Basic techniques for microbiology, Applied microbiology (fermentation). Thesis adviser for seven M.S. (April, 1990 to March, 1996; April, 1997 to March, 1999).
Associate professor (Lecturer)--Department of Biotechnology, Faculty of Engineering, Fukuyama University. Three technical courses for undergraduate students; Basic techniques for biotechnology, Basic techniques for microbiology, Applied microbiology (fermentation). Four classes for undergraduate students; English reading, Microbiology, Computer operations (Bioinformatics), Genome analysis. One class for M. S.; Advanced applied microbiology. Thesis adviser for seven M.S. and one Ph.D. (April, 1999 to March, 2002).
Associate professor (from April, 2003)--Department of Biotechnology, Faculty of Lifescience and Biotechnology, Fukuyama University. Three technical courses for undergraduate students; Basic techniques for biotechnology, Basic techniques for microbiology, Applied microbiology (fermentation). Four classes for undergraduate students; English reading, Biology II (Biochenistry), Microbiology, Computer operations (Bioinformatics), Matabolic Pathways, Genome analysis. One class for M. S.; Advanced applied microbiology. Thesis adviser for four M.S. and one Ph.D. (April, 2002 to date).
Associate professor (from April, 2004 to date)--Department of Biofunctional Chemistry, Faculty of Agriculture, Kobe University.
International Conferences:
Fujita, Y., Yoshida, K., Miwa, Y., Seki, S., and Fujimura, M. "Progress in sequencing of the sacXY(333°)-gnt(344°) region from B. subtilis chromosome." "Bacillus subtilis sequencing & Gene expression" meeting of the Biotechnology Program of the EU. INRA Jouy-en-Josas, Jouy-en-Josas, France. (24-26 November, 1994)
Yoshida, K., Miwa, Y., Fujimura, M., and Fujita, Y. "DNA sequencing of the sacXY(333°)-gnt(344°) region of the B. subtilis chromosome." 8th international conference on Bacillii. Stanford, CA. (8-12 July, 1995)
Yoshida, K., Shibayama, T., and Fujita, Y. "Structure and regulation of the iol operon of Bacillus subtilis." 9th international conference on Bacilli. UniversitEde Lausanne, Lausanne, Switzerland. (15-19 July, 1997)
Yoshida, K., and Fujita, Y. "Unique interaction of the iol repressor with its binding sites for regulation of the Bacillus subtilis iol divergon." International conference on Bacilli, Japan. Senri-chuo, Osaka, Japan. (12-15 July, 1998)
Yoshida, K., Ehrlich, S.D., Yamamoto, M., Nagakawa, E., and Fujita, Y. "Function analysis of the genes in the gnt-sacXY region of the Bacillus subtilis genome." European commission 6th European Bacillus subtilis gene function analysis meeting. University of Bayreuth, Bayreuth, Germany. (20-23 November, 1998).
Fujita, Y., Yoshida, K., Yamamoto, M., and Yamamoto, Y. "Basic characterization of integrational mutants and first level test on carbon source utilization and catabolite repression." 6th European meeting on systematic analysis of Bacillus subtilis genes. Dourdan, France. (1-4 May, 1999).
Yoshida, K., Fujita, Y., and Ehrlich, S.D. "Three asparagine synthetase genes of Bacillus subtilis." 10th international conference on Bacilli. Grand hotel Dino, Baveno, Itali. (27 June-1 July, 1999).
Yoshida, K., Yamaguchi, H., Matsunaga, M., Ogura, M., Tanaka, T, and Fujita, Y. "Transcriptome analysis of Bacillus subtilis by DNA microarray technique." 2nd Bacell network meeting. Greifswald, Germany. (6-8 October, 2000).
Yoshida, K., Tsurusaki, K., and Fujita, Y. "Identification of the unspecified gene products involved in inositol catabolism of Bacillus subtilis." International symposium, Functional Genomics of Bacillus subtilis. Rikkyo University, Tokyo, Japan (26-27 January, 2001).
Yoshida, K., Tsurusaki, K., and Fujita, Y. "Identification of the unspecified gene products involved in inositol catabolism of Bacillus subtilis." 11th International Conference on Bacilli, Functional Genomics of Gram-Positive Microorganisms. San Diego, CA (24-28 June, 2001).
Yoshida, K., Yamaguchi, H., and Fujita, Y. "Genome-wide screening of direct-targets of TnrA, a transcription factor for global nitrogen regulation in Bacillus subtilis." BACELL 2002 Meeting. Paterswolde, The Netherlands (3-7 May, 2002).
Yoshida, K., and Fujita, Y. "Systematic strategy to identify targets of unknown HTH regulators of Bacillus subtilis." 12th International Conference on Bacilli, Functional Genomics of Gram-pisitive Microorganisms, Baveno, Italy (22-27 June, 2003).
Yoshida, K. "Systematic strategy to identify targets of unknown HTH regulators of Bacillus subtilis." International Workshop for Escherichia coli towards New Biology in the 21st Century (15-17 October, 2003).
Yoshida, K. Igarashi, K., Morinaga, T., Kobayashi, K., Ashida, H., and Fujita, Y. "Transcription of Bacillus subtilis asnH operon under the dual control of AbrB and CodY is stabilized by the 5'-untranslated region of its own transcript containing a long sequence triplication." 13th International Conference on Bacilli, Functional Genomics of Gram-pisitive Microorganisms, San Diego, CA (12-16 June, 2005).
Yoshida, K., Kinehara, M., Ikeuti, M., Kurimoto, E., Kim, W.-S., Krishnan, H.B., and Ashida, H. "Functional analysis of NodD transcription factor paralogs of Shinorhizobium fredii USDA191 involved in regulation of the nodulation genes. Rikkyo international symposium "From bacteria to organelle", Tokyo (26 August, 2005).
"Functional analysis of NodD transcription factor paralogs of Sinorhizobium fredii USDA191 involved in regulation of the nodulation gene" 7th European Nitrogen Fixation Conference, Arhus, Denmark. (22-26 July, 2006).
"Promising application of inositol catabolism in Bacillus subtilis: Production of a drug candidate and a health-promoting food" BACELL 2007, Het Kasteel, Groningen, The Netherlands. (22 March, 2007).
"Genetic Modification of Bacillus subtilis for Production of D-chiro-Inositol, an Investigational Drug Candidate for Type 2 Diabetes and Polycystic Ovary Syndrome" I4th Conference on Functional Genomics of Gram-Positive Microorganisms; 14th International Conference on Bacilli, Green Park Hotel, Tirrenia (Pisa), Italy (24-28 June, 2007).
Invited seminars:
" Sequencing of the gnt-sacXY region (177 kb) of Bacillus subtilis genome and analysis of the iol operon." Laboratoire de Génétique Moléculaire et Cellulaire, INRA-CNRS (URA 1925)-INAPG, Thiverval-Grignon, France. (2 May, 1996).
"The genome sequencing project of Bacillus subtilis and its power in exploring new properties of microorganisms." Ernst-Moritz-Amdt-Uiversität Greifswald, Greifswald, Germany. (5 July, 1996).
"Sequencing of the gnt-sacXY region (177 kb) of Bacillus subtilis genome and analysis of the iol operon." Department of Microbiology, University of Newcastle, Newcastle upon Tyne, United Kingdom. (6 October, 1996).
"Reverse genetics after the whole genome sequencing: identification of a divergon involved in inositol catabolism in Bacillus subtilis and its regulation." Heidelberg Universität, Heidelberg, Germany. (24 November, 1998).
"An asparagine synthetase gene of Bacillus subtilis, asnO, is indispensable for sporulation." INRA, Jouy-en-Josas, France. (23 October, 2001).
"Reverse genetics of Bacillus subtilis." Department of Microbiology, University of Newcastle, Newcastle upon Tyne, United Kingdom. (2 May, 2002).
"Reverse genetics of Bacillus subtilis: Identification of functions of the genes involved in inositol catabolism." INRA-Grignon, France. (19 June, 2003).
"Systematic strategy to identify targets of unknown HTH regulators of Bacillus subtilis." INRA, Jouy-en-Josas, France. (20 June, 2003).
"Reverse genetics of Bacillus subtilis after the whole genome sequencing: crossing-over genetics, biochemistry, and bioinformatics" Graduate School of Nagoya Univ. Japan (13-14 September, 2004).
"Functional analysis of NodD transcription factor paralogs of Shinorhizobium fredii USDA191 involved in regulation of the nodulation genes." Dept. of Agronomy and Plant Genetic Research Unit, USDA-ARS, Univ. of Missouri, Columbia, MO. (20 June, 2005).
"Functional analysis of NodD transcription factor paralogs of Sinorhizobium fredii USDA191 involved in regulation of the nodulation gene" INRA-CNRS, Laboratoire des Interactions Plantes-Microorganismes, Toulouse, France. (28 July, 2006).
"Promising application of inositol catabolism in Bacillus subtilis: Production of a drug candidate and a health-promoting food" DSM Nutritional Products, Kaiseraugst Switzerland. (22 June, 2007).
"Functional analysis of NodD transcription factor paralogs of Sinorhizobium fredii USDA191 involved in regulation of the nodulation gene" Lyon Univ. (29 June, 2007).
"Promising application of inositol catabolism in Bacillus subtilis: Production of a drug candidate and a health-promoting food" GBB, Univ. of Groningen, The Netherlands. (5 November, 2007).
"Promising application of inositol catabolism in Bacillus subtilis" INRA, Jouy-en-Josas, France. (7 April, 2008).
1. Kobayashi, S., Yoshida, K., Ueda, K., Sakai, H., and Komano, T. (1988) DNA damage caused by ascorbate in the presence of Cu2+ induces mutations. Nucleic Acids Res., Symposium Series 19, 29-32.
2. Yoshida, K., Matsushima, Y., Sen, K., Sakai, H., and Komano, T. (1989) Insecticidal activity of a peptide containing the 30th to 695th amino acid residues of the 130-kDa protein of Bacillus thuringiensis var. israelensis. Agric. Biol. Chem. 53, 2121-2127.
3. Yoshida, K., Sen, K., Sakai, H., and Komano, T. (1989) Expression of the two 130-kDa protein genes of Bacillus thuringiensis var. israelensis in Bacillus subtilis. Agric. Biol. Chem. 53, 3033-3035.
4. Fujita, Y., Shindo, K., Miwa, Y., and Yoshida, K. (1991) Bacillus subtilis inositol dehydrogenase-encoding gene (idh): sequence and expression in Escherichia coli. Gene 108, 121-1255.
5. Komano, T., Yoshida, K., Sen, K., and Sakai, H. (1992) "Expression of insecticidal protein genes of Bacillus thuringiensis in bacteria" In Industrial Biotechnology (Malik, V. S. and Sridhar, P., eds) Oxford & IBH publishing Co. Pvt. Ltd., New Delhi, p.231-236.
6. Yoshisue, H., Yoshida, K., Sen, K., Sakai, H., and Komano, T. (1992) Effects of Bacillus thuringiensis var. israelensis 20-kDa protein on production of the Bti 130-kDa crystal protein in Escherichia coli. Biosci. Biotech. Biochem. 56, 1429-1433.
7. Yoshida, K., Fujita, Y., Mukai, E., Sen, K., Himeno, M., Sakai, H., and Komano, T. (1993) Importance of the central region of 130-kDa insecticidal proteins of Bacillus thuringiensis var. israelensis for their activity in vivo and in vitro. Biosci. Biotech. Biochem. 57, 584-590.
8. Yoshida, K., Fujita, Y., Mukai, E., Sen, K., Himeno, M., Sakai, H., and Komano, T. (1993) Binding of an engineered 130-kDa insecticidal protein of Bacillus thuringiensis var. israelensis to insect cell lines. Biosci. Biotech. Biochem. 57, 1200-1201.
9. Yoshida, K., Fujita, Y., and Sarai, A. (1993) Missense mutations in the Bacillus subtilis gnt repressor that diminish operator binding ability. J. Mol. Biol. 231, 167-174.
10. Yoshisue, H., Fukada, T., Yoshida, K., Sen, K., Krosawa, S., Sakai, H., and Komano, T. (1993) Transcriptional regulation of Bacillus thuringiensis subsp. israelensis mosquito larvicidal crystal protein gene cryIVA. J. Bacteriol. 175, 2750-2753.
11. Yoshida, K. (1993) Analysis of active regions of insecticidal proteins of Bacillus thuringinsis var. israelensis. Doctoral thesis of Kyoto University
12. Yoshida, K., Seki, S., and Fujita, Y. (1994) Nucleotide sequence and feature of the Bacillus licheniformis gnt operon. DNA Res. 1, 157-162.
13. Yoshida, K., Sano, H., Miwa, Y., Ogasawara, N., and Fujita, Y. (1994) Cloning and nucleotide sequencing of a 15 kb region of the Bacillus subtilis genome containing the iol operon. Microbiology 140, 2289-2298.
14. Yoshida, K., Sano, H., Seki, S., Oda, M., Fujimura, M., and Fujita, Y. (1995) Cloning and sequencing of a 29 kb region of the Bacillus subtilis genome containing the hut and wapA loci. Microbiology141, 337-343.
15. Yoshida, K., Seki, S., Fujimura, M., Miwa, Y., and Fujita, Y. (1995) Cloning and sequencing of a 36 kb region of the Bacillus subtilis genome between the gnt and iol operons. DNA Res. 2, 61-69.
16. Yoshida, K., Ohmori, H., Miwa, Y., and Fujita, Y. (1995) Bacillus subtilis gnt repressor mutants that diminish gluconate-binding ability. J. Bacteriol. 177, 4813-4816.
17. Yoshida, K., Miwa, Y., Ohmori, H., and Fujita, Y. (1995) Analysis of an insertional mutation (gntOi) of the Bacillus subtilisgnt operon affecting its expression level and gntOi suppressor mutations. Mol. Gen. Genet. 248, 581-591.
18. Yoshida, K., Fujimura, M., Yanai, N., and Fujita, Y. (1995) Cloning and sequencing of a 23-kb region of the Bacillus subtilis genome between the iol and hut operons. DNA Res. 2, 295-301.
19. Yoshida, K., Shindo, K., Sano, H., Seki, S., Fujimura, M., Yanai, N., Miwa, Y., and Fujita, Y. (1996) Sequencing of a 65 kb region of the Bacillus subtilis genome containing the lic and cel loci, and creation of a 177 kb contig covering the gnt-sacXY region. Microbiology 142, 3113-3123.
20. Yoshida, K., Aoyama, D., Ishio, I., Shibayama, T., and Fujita, Y. (1997) Organization and transcription of the myo-inositol operon, iol, of Bacillus subtilis. J. Bacteriol. 179, 4591-4598.
21. Kunst, F., Ogasawara, Moszer, I., and 148 other authors (Yoshida, K. as the 147th author) (1997) The complete genome sequence of the Gram-positive bacterium Bacillus subtilis. Nature 390, 249-256.
22. Fujita, Y., Yoshida, K., Miwa, Y., Yanai, N., Nagakawa, E., and Kasahara, Y. (1998) Identification and expression of the Bacillus subtilis fructose-bisphosphatase gene (fbp). J. Bacteriol. 180, 4309-4313.
23. Winstedt, L., Yoshida, K., Fujita, Y., and von Wachenfeldt, C. (1998) Cytochrome bd biosynthesis in Bacillus subtilis: characterization of the cydABCD operon. J. Bacteriol. 180, 6571-6580.
24. Yoshida, K., Shibayama, T., Aoyama, D., and Fujita, Y. (1999) Interaction of a repressor and its binding sites for regulation of the Bacillussubtilis iol divergon. J. Mol. Biol. 285, 917-929.
25. Yoshida, K., Fujita, Y., and Ehrlich, S. D. (1999) Three asparagine synthetase genes of Bacillus subtilis. J. Bacteriol. 181, 6081-6091.
26. Yoshida, K., Ishio, I., Nagakawa, E., Yamamoto, Y., Yamamoto, M., and Fujita, Y. (2000) Systematic study of gene expression and transcription organization in the gntZ-ywaA region of the Bacillus subtilis genome. Microbiology 146, 573-579.
27. Petit, M.-A., Yoshida, K., Fujita, Y., and Ehrlich, S. D. (2000) The 409 bp tandem repeat spanning genes yxaK and yxaL is absent from the Bacillus subtilis chromosome. Microbiology 146, 2091-2092.
28. Yoshida, K., Fujita, Y., and Ehrlich, S. D. (2000) An operon for a putative ATP-binding cassette transport system involved in acetoin utilization of Bacillus subtilis. J. Bacteriol. 182, 5454-5461.
29. Ishii, T., Yoshida, K., Terai, G., Fujita, Y., and Nakai, K. (2001) DBTBS: a database of Bacillus subtilis promoters and transcription factors. Nucleic Acids Res. 29, 278-280.
30. Yoshida, K., Kobayashi, K., Miwa, Y., Kang, C.-M., Matsunaga, M., Yamaguchi, H., Tojo, S., Yamamoto, M., Nishi, R., Ogasawara, N., Nakayama, T., and Fujita, Y. (2001) Combined transcriptome and proteome analysis as a powerful approach to study genes under glucose repression in Bacilus subtilis. Nucleic Acids Res. 29, 683-692.
31. Ogura, M., Yamaguchi, H., Yoshida, K., Fujita, Y., and Tanaka, T. (2001) DNA microarray analysis of Bacillus subtilis DegU, ComA and PhoP regulons: an approach to comprehensive analysis of B. subtilis two-component regulatory systems. Nucleic Acids Res. 29, 3804-3813.
32. Kobayashi, K., Ogura, M., Yamaguchi, H., Yoshida, K., Ogasawara, N., Tanaka, T., and Fujita, Y. (2001) Comprehensive DNA microarray analysis of Bacillus subtilis two-component regulatory systems. J. Bacteriol. 183, 7365-7370.
33. Yoshida, K., Yamamoto, Y., Omae, K., Yamamoto, M., and Fujita, Y. (2002) Identification of two myo-inositol transporter genes of Bacillus subtilis. J. Bacteriol. 184, 983-991.
34. Asai, K., Yamaguchi, H., Kang, C.-M., Yoshida, K., Fujita, Y., and Sadaie, Y. (2003) DNA microarray analysis of Bacillus subtilis sigma factors of extracytoplasmic function family. FEMS Microbiol Lett. 220,155-160.
35. Kobayashi, K., Ehrlich, S. D. et al. (2003) Essential Bacillus subtilis genes. Proc Natl Acad Sci U S A. 100,4678-4683.
36. Yoshida, K., Yamaguchi, H., Kinehara, M., Ohki, Y., Nakaura,Y., and Fujita. Y. (2003) Identification of additional TnrA-regulated genes of Bacillus subtilis associated with a TnrA box. Mol Microbiol. 49,157-165.
37. Doan, T., Servant, P., Tojo, S., Yamaguchi, H., Lerondel, G., Yoshida, K., Fujita, Y., and Aymerich, S. (2003) The Bacillus subtilis ywkA gene encodes a malic enzyme and its transcription is activated by the YufL/YufM two-component system in response to malate. Microbiology 149, 2331-2343.
38. Tojo, S., Matsunaga, M., Matsumoto, T., Kang, C.-M., Yamaguchi, H., Asai, K., Sadaie, Y., Yoshida, K., and Fujita, Y. (2003) Organization and expression of the Bacillus subtilis sigY operon. J. Biochem. 134, 935-946.
39. Yoshida, K., Yamaguchi, M., Ikeda, H., Omae, K., Tsurusaki, K., and Fujita, Y. (2004) The fifth gene of the iol operon of Bacillus subtilis, iolE, encodes 2-keto-myo-inositol dehydratase. Microbiology 150, 571-580.
40. Yoshida, K., Ohki, Y., Murata, M., Kinehara, M., Matsuoka, H., Satomura, T., Ohki, R., Kumano, M., Yamane, K., and Fujita, Y. (2004) Bacillus subtilis LmrA is a repressor of the lmrAB and yxaGH operons: identification of its binding site and functional analysis of lmrB and yxaGH. J. Bacteriol. 186, 5640-5648.
41. Tojo, S., Satomura, T., Morisaki, K., Yoshida, K., Hirooka, K., and Fujita, Y. (2004) Negative transcriptional regulation of the ilv-leu operon for biosynthesis of branched-chain amino acids through the Bacillus subtilis global regulator TnrA. J. Bacteriol. 186, 7971-7979.
42. Aoki, Y., Hashimoto, T., Yoshida, K., and Ashida, H. (2005) Suppressive effects of catechins on differentiation of 3T3-L1 preadipocytes. In Proceedings of 2004 International Conference on O-CHA (tea) Culture and Science, The Organizing Comittie of ICOS, 547-548.
43. Kubo, M., Sakane, I., Sawamura, S., Yoshida, K., and Ashida, H. (2005) Black tea (Camellia sinensis) suppresses hyperglycemia in STZ- induced diabetic rats. In Proceedings of 2004 International Conference on O-CHA (tea) Culture and Science, The Organizing Comittie of ICOS, 561-562.
44. Fukuda, I., Sakane, I., Nishiumi, S., Shirasugi, S., Sawamura, S., Kanazawa, K., Yoshida, K., and Ashida, H. (2005) Tea has the potential to reduce the dioxin risk. In Proceedings of 2004 International Conference on O-CHA (tea) Culture and Science, The Organizing Comittie of ICOS, 594-595.
45. Harvie, D.R., Andreini, C., Cavallaro, G., Meng, W., Connolly, B.A., Yoshida, K., Fujita, Y., Harwood, C.R., Radford, D.S., Tottey, S., Cavet, J.S., and Robinson, N.J. (2006) Predicting metals sensed by ArsR-SmtB repressors: allosteric interference by a non-effector metal. Mol. Microbiol. 59, 1341-1356.
46. Yoshida, K., Yamaguchi, M., Morinaga, T., Ikeuchi, M., Kinehara, M., and Ashida, H. (2006) Genetic modification of Bacillus subtilis for production of D-chiro-inositol, an investigational drug candidate for treatment of type 2 diabetes and polycystic ovary syndrome. Appl. Environ. Microbiol. 72, 1310-1315.
47. Nishiumi, S., Hosokawa, K., Mukai, R., Fukuda, I., Hishida, A., Iida, O., Yoshida, K., and Ashida, H. (2006) Screening of indigenous plants from Japan for modulating effects on transformation of the aryl hydrocarbon receptor. Asian. Pac. J. Cancer. Prev. 7, 208-220.
48. Morinaga, T., Yamaguchi, M., Makino, Y., Nanamiya, H., Takahashi, K., Yoshikawa, H., Kawamura, F., Ashida, H., and Yoshida, K. (2006) Functional myo-inositol catabolic genes of Bacillus subtilis Natto are involved in depletion of pinitol in Natto (fermented soybean). Biosci. Biotechnol. Biochem. 70, 1913-1920.
49. Yoshida, K., Kim, W.S., Kinehara, M., Mukai, R., Ashida, H., Ikeda, H., Fujita, Y., and Krishnan, H.B. (2006) Identification of a functional 2-keto-myo-inositol dehydratase gene of Sinorhizobium fredii USDA191 required for myo-inositol utilization. Biosci. Biotechnol. Biochem. 70, 2957-2964.
50. Hirooka, K., Kunikane, S., Matsuoka, H., Yoshida, K., Kumamoto, K., Tojo, S., and Fujita, Y. (2007) Dual regulation of the Bacillus subtilis regulon comprising the lmrAB and yxaGH operons and yxaF gene by two transcriptional repressors, LmrA and YxaF, in response to flavonoids. J. Bacteriol. 189, 5170-5182.
51. Fukuda, I., Mukai, R., Kawase, M., Yoshida, K., and Ashida, H. (2007) Interaction between the aryl hydrocarbon receptor and its antagonists, flavonoids. Biochem. Biophys. Res. Commun. 359, 822-827.
52. Yap, A., Nishiumi, S., Yoshida, K., and Ashida, H. (2007) Rat L6 myotubes as an in vitro model system to study GLUT4-dependent glucose uptake stimulated by inositol derivatives. Cytotechnol. 55, 103-108.
53. Nishiumi, S., Yoshida, K., and Ashida, H. (2007) Curcumin suppresses the transformation of an aryl hydrocarbon receptor through its phosphorylation. Arch. Biochem. Biophys. 466, 267-273.
54. Nishiumi, S., Yamamoto, N., Kodoi, R., Fukuda, I., Yoshida, K., and Ashida, H. (2008) Antagonistic and agonistic effects of indigoids on the transformation of an aryl hydrocarbon receptor. Arch. Biochem. Biophys. 470, 187-199.
55. Yoshida, K., Yamaguchi, M., Morinaga, T., Kinehara, M., Ikeuchi, M., Ashida, H., and Fujita, Y. (2008) myo-Inositol Catabolism in Bacillus subtilis. J. Biol. Chem. 283, 10415-10424.
56. Kada, S., Yabusaki, M., Kaga, T., Ashida, H., and Yoshida, K. (2008) Identification of two major ammonia-releasing reactions involved in secondary natto fermentation. Biosci. Biotechnol. Biochem. 272, 1869-1876.
57. Ueda, M., Nishiumi, S., Nagayasu, H., Fukuda, I., Yoshida, K., and Ashida H. (2008) Epigallocatechin gallate promotes GLUT4 translocation in skeletal muscle. Biochem. Biophys. Res. Commun. 377, 2862-2890.
58. Mukai, R., Fukuda, I., Nishiumi, S., Natsume, M., Osakabe, N., Yoshida, K., and Ashida H. (2008) Cacao polyphenol extract suppresses transformation of an aryl hydrocarbon receptor in C57BL/6 mice. J. Agric. Food Chem. 56, 10399-10405.
last updated; on 26th December, 2008, by Ken-ichi Yoshida (kenyoshi@kobe-u.ac.jp).