2018
Suzuki E, Matsuda T, Kawamoto T, Takahashi H, Mieda Y, Matsuura Y, Takai T, Kanno A, Kimura-Koyanagi M, Asahara S.-i, Inoue H, Ogawa W, Kido Y.
Docosahexaenoic acid reduces palmitic acid-induced endoplasmic reticulum stress in pancreatic β cells.
Kobe J.Med.Sci. in press
Takai T, Matsuda T, Matsuura Y, Inoue K, Suzuki E, Kanno A, Kimura-Koyanagi M, Asahara S.-i, Hatano N, Ogawa W, Kido Y.
Casein kinase 2 phosphorylates and stabilizes C／EBPβ in pancreatic β cells.
Biochem. Biophys. Res. Commun. 497:451-456
2017
Bartolomé A, García-Aguilar, Asahara S, Kido Y, Guillén C, Pajvani UB, Benito M. MTORC1 Regulates both General Autophagy and Mitophagy Induction after Oxidative Phosphorylation Uncoupling. Mol Cell Biol 37:e0044-17
Kawada Y, Asahara S, Sugiura Y, Sato A, Furubayashi A, Kawamura M, Bartolome A, Terashi-Suzuki E, Takai T, Koyanagi-Kimura M, Matsuda T, Hashimoto N, Kido Y. Histone deacetylase regulates insulin signaling via two pathways in pancreatic β cells. PLoS ONE 12:e0184435
Watanabe H, Inaba Y, Kimura K, Asahara S, Kido Y, Matsumoto M, Motoyama T, Tachibana N, Kaneko S, Kohno M, Inoue H. Dietary Mung Bean Protein Reduces Hepatic Steatosis, Fibrosis, and Inflammation in Male Mice with Diet-induced, Non-alcoholic Fatty Liver Disease. J Nutr 147:52-60
2016
Sakai M, Tsujimura T, Yagi T, Yano H, Mitsushima M, Unoki-Kubota H, Kaburagi Y, Inoue H, Kido Y, Kasuga M, Matsumoto M. The GCN5-CITED2-PKA signalling module controls hepatic glucose metabolism through a cAMP-induced substrate switch. Nat Commun 7:13147
Kimura K, Tanida M, Nagata N, Inaba Y, Watanabe H, Nagashimada M, Ota T, Asahara S, Kido Y, Matsumoto M, Toshinai K, Nakazato M, Shibamoto T, Kaneko S, Kasuga M, Inoue H. Centra insulin-action activates Kupffer cells by suppressing hepatic vagal activation through nicotinic alpha 7 acetylcholine receptor. Cell Rep 14:2362-74
2015
Matsuda T, Iwasaki M, Yoshioka N, Hirota Y, Hamaguchi H, Kido Y, Sakaguchi K, Ogawa W. A case of hemiplegia with hypoglycemia possibly associated with hemodynamic change. Diabetol Int. 6: 336-340
Nakarai C, Osawa K, Akiyama M, Matsubara N, Ikeuchi H, Yamano T, Hirota S, Tomita N, Usami M, Kido Y. Expression of AKR1C3 and CNN3 as markers for detection of lymph node metastasis in colorectal cancer. Clin Exp Med 15: 333-341
Asahara S, Etoh H, Inoue H, Teruyama K, Shibutani Y, Ihara Y, Kawada Y, Bartolome A, Hashimoto N, Matsuda T, Koyanagi-Kimura M, Kanno A, Hirota Y, Hosooka T, Nagashima K, Nishimura W, Inoue H, Matumoto M, Higgins MJ, Yasuda K, Inagaki N, Seino S, Kasuga M, Kido Y. Paternal allelic mutation at the Kcnq1 locus reduces pancreatic β cell mass via epigenetic modification of Cdkn1c. Proc Natl Acad Sci USA. 112: 8332-8337
Matsuda T, Takahashi H, Mieda Y, Shimizu S, Kawamoto T, Matsuura Y, Takai T, Suzuki E, Koyanagi-Kimura M, Asahara S, Bartolome A, Yokoi N, Inoue H, Ogawa W, Seino S, Kido Y. Regulation of pancreatic β cell mass by cross-interaction between CCAAT enhancer binding protein β induced by endoplasmic reticulum stress and AMP-activated protein kinase activity. PLoS ONE. 10: e0130757
Cook JR, Langlet F, Kido Y, Accili D. Pathogenesis of selective insulin resistance in isolated hepatocytes. J Biol. Chem. 290:13972-80
Inaba Y, Furutani T, Kimura K, Watanabe H, Haga S, Kido Y, Matsumoto M, Yamamoto Y, Harada K, Kaneko S, Oyadomari S, Ozaki M, Kasuga M, Inoue H. Growth arrest and DNA damage-inducible 34 regulates liver regeneration in hepatic steatosis in mice. Hepatology 61:1343-56
Kanno A, Asahara S, Masuda K, Matsuda T, Kimura-Koyanagi M, Seino S, Ogawa W, Kido Y. Compensatory hyperinsulinemia in high-fat diet-induced obese mice is associated with enhanced insulin translation in islets. Biochem. Biophys. Res. Commun. 458: 681-686
2014
Bartolomé A, Kimura-Koyanagi M, Asahara S, Guillén C, Inoue H, Teruyama K, Shimizu S, Kanno A, García-Aguilar A, Koike M, Uchiyama Y, Benito M, Noda T, Kido Y. Pancreatic β cell failure mediated by mTORC1 hyperactivity and autophagic impairment. Diabetes 63: 2996-3008
Yoshida Y, Fuchita M, Kimura-Koyanagi M, Kanno A, Matsuda T, Asahara S, Hashimoto N, Isagawa T, Ogawa W, Aburatani H, Noda T, Seino S, Kasuga M, Kido Y．Contribution of insulin signaling to the regulation of pancreatic beta-cell mass during the catch-up growth period in a low birth weight mouse model．Diabetol Int 5: 43-52
2013
Kimura K, Nakamura Y, Inaba Y, Matsumoto M, Kido Y, Asahara S, Matsuda T, Watanabe H, Maeda A, Inagaki F, Mukai C, Takeda K, Akira S, Ota T, Nakabayashi H, Kaneko S, Kasuga M, Inoue H. Histidine augments the suppression of hepatic glucose production by central insulin action. Diabetes 62: 2266-2277
Shibutani Y, Asahara S, Teruyama K, Inoue H, Matsuda T, Seino S, Kido Y. Constitutive activation of Rac1 in pancreatic β cells facilitates F-actin depolymerization but exerts no influence on the increase of pancreatic β cell mass and facilitation of insulin secretion. Kobe J Med Sci 59:72-80
Asahara S, Shibutani Y, Teruyama K, Inoue H, Kawada Y, Etoh H, Matsuda T, Kimura-Koyanagi M, Hashimoto N, Sakahara M, Fujimoto W, Takahashi H, Ueda S, Hosooka T, Satoh T, Inoue H, Matsumoto M, Aiba A, Kasuga M, Kido Y Rac1 regulates glucose-stimulated insulin secretion via modulation of F-actin. Diabetologia 56:1088-1097
2012
Osawa K, Nakarai C, Akiyama M, Hashimoto R, Tsutou A, Takahashi J, Takaoka Y, Kawamura S, Shimada E, Tanaka K, Kozuka M, Yamamoto M, Kido Y Association between polymorphisms is UDP-glucuronosyltransferase 1A6 and 1A7 and colorectal cancer risk. Asian Pac J Cancer Prev 13: 2311-2314
Nakarai C, Osawa K, Matsubara N, Ikeuchi H, Yamano T, Okamura S, Kamosida S, Tsutou A, Takahashi J, Ejiri K, Hirota S, Tomita N, Kido Y
Significance of ELF3 mRNA expression for detection of lymph node metastasis of colorectal cancer. Anticancer Res 32: 3753-3758
Shimizu S, Hosooka T, Matsuda T, Asahara S, Koyanagi-Kimura M, Kanno A, Bartolome A, Etoh H, Fuchita M, Teruyama K, Takahashi H, Inoue H, Mieda Y, Hashimoto N, Seino S, Kido Y. DPP4 inhibitor vildagliptin preserves beta cell mass through amelioration of ER stress in C/EBPB transgenic mice. J Mol Endocrinol 49:125-135
Takano S, Kaji H, Hayashi F, Higashiguchi K, Joukei S, Kido Y, Takahashi J, Osawa K. A calculation model for serum ionized calcium based on an equilibrium equation for complexation. Analytical Chemistry Insights 7:23-30
Hara K, Yasuda H, Arai T, Miyoshi S, Kubokawa O, Mori H, Akisaki T, Kido Y, Yokono K, Akita H. A case of an elderly patient with slowly progressive type 1 diabetes who developed severe nonocclusive mesenteric ischemia without predisposing events. Internal Medicine 51:1065-1068
Sakai M, Matsumoto M, Tsujimura T, Yongheng C, Inagaki K, Yasuda K, Noguchi T, Hosooka T, Inoue H, Takazawa K, Kido Y, Hiramatsu R, Matsuki Y, Kasuga M. CITED2 links hormonal signaling to PGC-1α acetylation in regulation of gluconeogenesis. Nat Med. 18: 612-617
Kimura K, Yamada T, Matusmoto M, Kido Y, Hosooka T, Asahara S, Matsuda T, Ota T, Watanabe H, Sai Y, Miyamoto K, Kaneko S, Kasuga M, Inoue H. Endoplasmic Reticulum Stress Inhibits STAT3-dependent Suppression of Hepatic Gluconeogenesis via Dephosphorylation and Deacetylation. Diabetes 61:61-73
2011
Koyanagi M, Asahara S, Matsuda T, Hashimoto N, Shigeyama Y, Shibutani Y, Kanno A, Fuchita M, Mikami T, Hosooka T, Inoue H, Matsumoto M, Koike M, Uchiyama Y, Noda T, Seino S, Kasuga M, Kido Y. Ablation of TSC2 enhances insulin secretion by increasing the number of mitochondria through activation of mTORC1. PLoS ONE 6: e23238
2010
Osawa K, Miyaishi A, Uchino K, Osawa Y, Inoue N, Nakarai C, Tsutou A, Kido Y, Yoshimura M, Tsubota N, Takahashi J. APEX1 Asp148Glu gene polymorphism is a risk factor for lung cancer in relation to smoking in Japanese. Asian Pac J Cancer Prev 11:1181-1186
Matsuda T, Kido Y, Asahara S, Kaisho T, Tanaka T, Hashimoto N, Shigeyama Y, Takeda A, Inoue T, Shibutani Y, Koyanagi M, Hosooka T, Matsumoto M, Inoue H, Uchida T, Koike M, Uchiyama Y, Akira S, Kasuga M. Ablation of C/EBPβ alleviates ER stress and pancreatic β cell failure through the GRP78 chaperone in mice. J. Clin. Invest. 120:115-126
2009
Inoue T, Kido Y, Asahara S, Matsuda T, Shibutani Y, Koyanagi M, Kasuga M. Effect of intrauterine undernutrition during late gestation on pancreatic β cell mass. Biomed. Res. 30:325-330
Asahara S, Matsuda T, Kido Y, Kasuga M. Increased ribosomal biogenesis induces pancreatic β cell failure in mice model of type 2 diabetes. Biochem. Biophys. Res. Commun. 381: 367-371
2008
Takeda A, Kido Y, Hashimoto N, Noda T, Kasuga M. Pancreatic β Cell Mass Preserved in Heterozygous PDK1 Knockout Mice. Kobe J Med Sci 54: E183-190
Matsuda T, Kido Y, Uchida T, Kasuga M Reduced insulin signaling and endoplasmic reticulum stress act synergistically to deteriorate pancreatic beta cell function. Kobe J Med Sci 54: E114-121
Shigeyama Y, Kobayashi T, Kido Y, Hashimoto N, Asahara S, Matsuda T, Takeda A, Inoue T, Shibutani Y, Koyanagi M, Uchida T, Inoue M, Hino O, Kasuga M, Noda T Biphasic response of pancreatic β cell mass to ablation of TSC2 in mice. Mol Cell Biol 28:2971-2979
2007
Nakawatase Y, Taru C, Tsutou A, Shiotani H, Kido Y, Ohara T, Ogawa W, Miyawaki I. Development of an evaluation scale for self-management behavior related to physical activity of type 2 diabetic patients. Diabetes Care 30:2843-2848
Kim JJ, Kido Y, Scherer PE, White MF, Accili D. Analysis of compensatory β-cell response in mice with combined mutations of Insr and Irs2. Am J Physiol Endocrinol Metab 292:E1694-E1701
Strom A, Bonal C, Ashley-Padan R, Hashimoto N, Campos ML, Trumpp A, Noda T, Kido Y, Real FX, Thorel F, Herrera PL. Unique mechanism of growth regulation and tumor suppression upon Apc inactivation in the pancreas. Development 134:2719-2725
2006
Hashimoto N, Kido Y, Uchida T, Asahara S, Shigeyama Y, Matsuda T, Takeda A, Tsuchihashi D, Nishizawa A, Ogawa W, Fujimoto Y, Okamura H, Arden KC, Herrera PL, Noda T, Kasuga M. Ablation of PDK1 in pancreatic β cells induces diabetes as a result of loss of β-cell mass. Nat. Genet. 38:589-593
2005
Uchida T, Nakamura T, Hashimoto N, Matsuda T, Kotani K, Sakaue H, Kido Y, Hayashi Y, Nakayama KI, White MF, Kasuga M. Deletion of Cdkn1b ameliorates hyperglycemia by maintaining compensatory hyperinsulinemia in diabetic mice. Nat. Med. 11:175-182
Hashimoto N, Kido Y, Uchida T, Matsuda T, Suzuki K, Inoue H, Matsumoto M, Ogawa W, Maeda S, Fujihara H, Ueta Y, Uchiyama Y, Akimoto K, Ohno S, Noda T, Kasuga M. PKCλ regulates glucose-induced insulin secretion through modulation of gene expression in pancreatic β cells. J. Clin. Invest. 115:138-145
Yutsudo Y, Kido Y, Okabayashi Y, Matsumoto M, Ogawa W, Ohba M, Kuroki T, Kasuga M. Protein kinase Calpha is implicated in cholecystokinin-induced activation of 70-kd S6 kinase in AR42J cells. Pancreas 30:50-53
2004
Inoue H, Ogawa W, Ozaki M, Haga S, Matsumoto M, Furukawa K, Hashimoto N, Kido Y, Mori T, Sakaue H, Teshigawara K, Jin S, Iguchi H, Hiramatsu R, LeRoith D, Takeda K, Akira S, Kasuga M. Role of STAT-3 in regulation of hepatic gluconeogenic genes and carbohydrate metabolism in vivo. Nat. Med. 10:168-174
2003
Nogami M, Yamazaki M, Watanabe H, Okabayashi Y, Kido Y, Kasuga M, Sasaki T, Maehama T, Kanaho Y. Requirement of autophosphorylated tyrosine 992 of EGF receptor and its docking phospholipase Cγ1 for membrane ruffle formation. FEBS lett. 536:71-76
Ochi F, Fujii M, Sakai T, Sugano M, Oshiro K, Okabayashi Y, Mita M, Kido Y. A case of acute pancreatitis associated with cationic trypsinogen N29T mutation. Pancreas 27: 199-201
2002
Kitamura T, Nakae J, Kitamura Y, Kido Y, Biggs III WH, Wright CW, White MF, Arden KC, Accili D. The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic β cell growth. J. Clin. Invest. 110:1839-1847
Xuan S, Kitamura T, Nakae J, Politi K, Kido Y, Fisher PE, Morroni M, Cinti S, White MF, Herrera PL, Accili D, Efstratiadis A. Defective insulin secretion in pancreaticβcells lacking type 1 IGF receptor. J. Clin. Invest. 110:1011-1019
Kido Y, Nakae J, Hribal ML, Xuan S, Efstratiadis A, Accili D. Effects of mutations in the insulin-like growth factor signaling system on embryonic pancreas development and β-cell compensation to insulin resistance. J. Biol. Chem. 277:36740-36747
Poy MN, Yang Y, Rezaei K, Fernstrom MA, Lee AD, Kido Y, Erickson SK, Najar SM. CEACAM1 regulates insulin clearance in liver. Nat. Genet. 30:270-276
2001
Kitamura T, Kido Y, Nef S, Merenmies J, Parada LF, Accili D. Preserved Pancreatic beta-Cell Development and Function in Mice Lacking the Insulin Receptor-Related Receptor. Mol. Cell. Biol. 21:5624-5630
Kim JJ, Park BC, Kido Y, Accili D. Mitogenic and Metabolic Effects of Type I IGF Receptor Overexpression in Insulin Receptor-Deficient Hepatocytes. Endocrinology 142:3354-3360
2000
Kido Y, Philippe N, Schaffer AA, Accili D. Genetic modifiers of the insulin resistance phenotype in mice. Diabetes 49:589-596
Kido Y, Burks DJ, Withers D, Bruning JC, Kahn CR, White MF, Accili D. Tissue-specific insulin resistance in mice with mutations in the insulin receptor, IRS-1, and IRS-2. J. Clin. Invest. 105:199-205
2018
BIA(bioelectrical impedance analysis)法で定量した日本人糖尿病患者の体組成と栄養評価法の検討, 松尾真里, 宇佐美眞, 三好真琴, 上野真波, 梶田歩, 山下勇人, 植村弥希子, 井上岳人, 内田絢子, 芝唯, 三ヶ尻礼子, 山本育子, 戸田明代, 高橋路子, 木戸良明，坂本憲広，栄養‐Trends of Nutrition‐, Vol3 No.1:45-50
2017
週１回製剤のアンメットニーズ探索，松田友和，鈴木江美，高井智子，野村和弘,名田高幸,木戸良明，横井峰人，Prog.Med.，37: 1113-1122
2013
短時間および長時間作用型GLP-1受容体作動薬が食行動に及ぼす影響，木戸良明，城内繭子，別當憲子，穴倉弘枝，南美樹，松田友和，宇佐美勝，池田弘毅，池田正毅，日本病態栄養学会誌，16: 407-414
2008
多留ちえみ、中渡瀬友里、傅秋光、田守義和、野口哲也、木戸良明、大原毅、小川渉、宮脇郁子 2型糖尿病患者の臨床背景別の食事自己管理行動の実施状況における特徴 糖尿病 51: 125-138
2005
多留ちえみ、宮脇郁子、矢田真美子、宮田哲、木戸良明、井上朋子、谷口洋 2型糖尿病患者の食事療法負担感尺度の開発 糖尿病 48: 435-442