神戸大学大学院医学系研究科　病態解析学領域　病態代謝学分野

研究業績

48.
Kuno H, Tsuji N, Kobayashi K, Takumi T, Tachibana Y.
Intralaminar talams relays basal ganglia output to the insular cortex to drive tic generation.
Cell reports (2026):117272.
神戸大プレスリリース：https://www.kobe-u.ac.jp/ja/news/article/20260423-67758/


47.
Sotani N, Kusuhara S, Nishisyo R, Kuno H, Shima H, Haruwaka K, Mori Y, Kishi M, Furuyashiki T, Kobayashi K, Wake H, Takumi T, Nakamura M, Tachibana Y.
Transpupillary in vivo two-photon imaging reveals enhanced surveilance oe retinal microgria in diabetic mice.
PNAS (2025) 122(41):e2426241122.
神戸大プレスリリース：https://www.kobe-u.ac.jp/ja/news/article/20251007-67149/


46.
Sato F, Tsutsumi Y, Oka A, Furuta T, Sohn J, Oi Y, Amano M, Morita A, Uchino K, Kato T, Bae Y, Tachibana Y, Sessle B, Yoshida A.
Projections from Rejions of the Cerebellar Nuclei Receiving aw Muscle Proprioceptive Signals to Trigeminal Motoneurons and Their Premotoneurons in the Rat Pons and Medulla.
Cerebellum (2025) 24(4):113.

45.
Katagiri T, Nakamura S, Tachibana Y, Nakayama K, Mochizuki A, Dantsuji M, Baba K, Inoue T.
Tooth loss-associated neuroplasticity of mastication-related motor cortical neurons.   
J Oral Biosci (2025) 67(1).

44.
Tsutsumi Y, Morita Y, Sato F, Furuta T, Uchino K, Sohn J, Haque T, Bae YC, Niwa H, Tachibana Y,
Yoshida A.   
Cerebellar nuclei receiving orofacial proprioceptive signals through the mossy fiber pathway from the supratrigeminal nucleus in rats.   
Cerebellum (2024) 23(5): 1795-1810.

43.
Kato D, Aoyama Y, Nishida K, Takahashi Y, Sakamoto T, Takeda I, Tatematsu T, Go S, Saito Y, Kunishima S, Cheng J, Hou L, Tachibana Y, Sugio S, Kondo R, Eto F, Sato S, Moorhouse AJ, Yao I, Kadomatsu K, Setou M, Wake H.   
Regulation of lipid synthesis in myelin modulates neural activity and is required for motor learning.   
Glia (2023) 71(11): 2591-2608.

42.
Tsutsumi Y, Sato F, Furuta T, Uchino K, Moritani M, Bae YC, Kato T, Tachibana Y, Yoshida A.   
The cerebellar cortex receives orofacial proprioceptive signals from the supratrigeminal nucleus via the mossy fiber pathway in rats.   
Cerebellum (2023) 22(4): 663-679.

41.
Hasegawa Y, Sakuramoto A, Suzuki T, Sakagami J, Shiramizu M, Tachibana Y, Kishimoto H, Ono Y, Ono T.
Emotional modulation of cortical activity during gum chewing: A functional near-infrared spectroscopy study.
Front Neurosci (2022) 16: 964351.

40.
Yoshioka Y, Tachibana Y, Uesaka T, Hioki H, Fukumoto T, Enomoto H.   
Uts2b is a microbiota-regulated gene expressed in vagal afferent neurons connected to enteroendocrine cells producing cholecystokinin.   
Biochem Biophys Res Commun (2022) 608: 66-72.

39.
Hirata Y, Nomura K, Kato D, Tachibana Y, Niikura T, Uchiyama K, Hosooka T, Fukui T, Oe K, Kuroda R, Hara Y, Adachi T, Shibasai K, Wake H, Ogawa W.   
A Piezo1/KLF15/IL-6 axis mediates immobilization-induced muscle atrophy.   
J Clin Invest (2022) 132(10): 1-13.

38.
Yoshida A, Inoue M, Sato F, Morita Y, Tsutsumi Y, Furuta T, Uchino K, Akhter F, Bae YC, Tachibana Y, Inoue T.   
Efferent and afferent connections of supratrigeminal neurons conveying orofacial muscle proprioception in rats.
Brain Struct Funct (2022) 227(1): 111-129.

37.
Tsutsumi Y, Mizuno Y, Haque T, Sato F, Furuta T, Oka A, Moritani M, Bae YC, Yamashiro T, Tachibana Y,
Yoshida A.
Widespread corticopetal projections from the oval paracentral nucleus of the intralaminar thalamic nuclei conveying orofacial proprioception in rats.   
Brain Struct Funct (2021) 226(4): 1115-1133.

36.
Okada T, Kato D, Nomura Y, Obata N, Quan X, Morinaga A, Yano H, Guo Z, Aoyama Y, Tachibana Y, Moorhouse AJ, Matoba O, Takiguchi T, Mizobuchi S, Wake H.   
Pain induces stable, active microcircuits in the somatosensory cortex that provide a new therapeutic target.
Sci Adv (2021) 7(12): eabd8261.

35.
Uemura Y, Haque T, Sato F, Tsutsumi Y, Ohara H, Oka A, Furuta T, Bae YC, Yamashiro T, Tachibana Y,
Yoshida A.  
Proprioceptive thalamus receiving forelimb and neck muscle spindle inputs via the external cuneate nucleus in the rat.   
Brain Struct Funct (2020) 225(7): 2177-2192.

34.
Sato F, Kado S, Tsutsumi Y, Tachibana Y, Ikenoue E, Furuta T, Uchino K, Bae YC, Uzawa N, Yoshida A.   
Ascending projection of jaw-closing muscle-proprioception to the intralaminar thalamic nuclei in rats.   
Brain Res (2020) 1739: 146830.

33.
Kato D, Wake H, Lee PR, Tachibana Y, Ono R, Sugio S, Tsuji Y, Tanaka YH, Tanaka YR, Masamizu Y, Hira R, Moorhouse AJ, Tamamaki N, Ikenaka K, Matsukawa N, Fields RD, Nabekura J, Matsuzaki M.   
Motor learning requires myelination to reduce asynchrony and spontaneity in neural activity.   
Glia (2020) 68(1): 193-210.

32.
Haruwaka K, Ikegami A, Tachibana Y, Ohno N, Konishi H, Hashimoto A, Matsumoto M, Kato D, Ono R, Kiyama H, Moorhouse AJ, Nabekura J, Wake H.   
Dual microglia effects on blood brain barrier permeability induced by systemic inflammation.   
Nat Commun (2019) 10(1): 5816.

31.
Murakami J, Tachibana Y, Akiyama S, Kato T, Taniguchi A, Nakajima Y, Shimoda M, Wake H, Kano Y, Takada M, Nambu A, Yoshida A.   
Oral splint ameliorates tic symptoms in patients with Tourette syndrome.   
Mov Disord (2019) 34(10): 1577-1578.

30.
Hikosaka O, Kim HF, Amita H, Yasuda M, Isoda M, Tachibana Y, Yoshida A.   
Direct and indirect pathways for choosing objects and actions.   
Eur J Neurosci (2019) 49(5): 637-645.

29.
Akiyoshi R, Wake H, Kato D, Horiuchi H, Ono R, Ikegami A, Haruwaka K, Omori T, Tachibana Y, Moorhouse AJ, Nabekura J.   
Microglia enhance synapse activity to promote local network synchronization.   
eNeuro (2018) 5(5): 0088-18.

28.
Tsutsumi Y, Tachibana Y, Sato F, Furuta T, Ohara H, Tomita A, Fujita M, Moritani M, Yoshida A.   
Cortical and subcortical projections from granular insular cortex receiving orofacial proprioception.   
Neurosci (2018) 388: 317-329.

27.
Ikenoue E, Akhter F, Tsutsumi Y, Sato F, Ohara H, Uchino K, Furuta T, Tachibana Y, Yoshida A.   
Transcortical descending pathways through granular insular cortex conveying orofacial proprioception.   
Brain Res (2018) 1687: 11-19.

26.
Iwamuro H, Tachibana Y, Ugawa Y, Saito N, and Nambu A.
Information processing from the motor cortices to the subthalamic nucleus and globus pallidus and their somatotopic organizations revealed electrophysiologically in monkeys.
Eur J Neurosci (2017) 46(11): 2684-2701.

25.
Sato F, Uemura Y, Kanno C, Tsutsumi Y, Tomita A, Oka A, Kato T, Uchino K, Murakami J, Haque T, Tachibana Y, and Yoshida A.
Thalamo-insular pathway conveying orofacial muscle proprioception in the rat.
Neurosci (2017) 365: 158-178.

24.
Yoshida A, Fujio T, Sato F, Ali MSS, Haque T, Ohara H, Moritani M, Kato T, Dostrovsky JO, and Tachibana Y.
Orofacial proprioceptive thalamus of the rat.
Brain Struct Funct (2017) 222(6): 2655-2669.

23.
Hasegawa Y, Tachibana Y, Ono T, and Kishimoto H.
Flavour-enhanced cortisol release during gum chewing.
PLoS One (2017) 12(4): e0173475.

22.
Shouno O, Tachibana Y, Nambu A, and Doya K.
Computational model of recurrent subthalamo-pallidal circuit for generation of parkinsonian oscillations.
Front Neuroanat (2017) 11: 21.

21.
Fujio T, Sato F, Tachibana Y, Kato T, Tomita A, Higashiyama K, Ono T, Maeda Y, and Yoshida A.
Revisiting the supratrigeminal nucleus in the rat.
Neurosci (2016) 324: 307-320.

20.
Ohara H, Tachibana Y, Fujio T, Takeda-Ikeda R, Sato F, Oka A, Kato T, Ikenoue E, Yamashiro T, and Yoshida A.
Direct projection from the lateral habenula to the trigeminal mesencephalic nucleus in rats.
Brain Res (2016) 1630: 183-197.

19.
Nambu A, and Tachibana Y.
Mechanism of parkinsonian neuronal oscillations in the primate basal ganglia: some considerations based on our recent work.
Front Syst Neurosci (2014) 8: 74.

18. Nambu A, Tachibana Y, and Chiken S.
Cause of parkinsonian symptoms: Firing rate, firing pattern or dynamic activity changes?
Basal Ganglia (2015) 5(1): 1-6.

17.
Hasegawa Y, Tachibana Y, Sakagami J, Zhang M, Urade M, and Ono T.
Flavor-enhanced modulation of cerebral blood flow during gum chewing.
PLoS One (2013) 8(6): e66313.

16.
Tachibana Y (CA), and Hikosaka O.
The primate ventral pallidum encodes expected reward value and regulates motor action.
Neuron (2012) 76(4): 826-837.

15.
Tachibana Y (CA), Iwamuro H, Kita H, Takada M, and Nambu A.
Subthalamo-pallidal interactions underlying parkinsonian neuronal oscillations in the primate basal ganglia.
Eur J Neurosci (2011) 34(9): 1470-1484.

14.
Nambu A, Chiken S, Shashidharan P, Nishibayashi H, Ogura M, Kakishita K, Tanaka S, Tachibana Y, Kita H, and Itakura T.
Reduced pallidal output causes dystonia.
Front Syst Neurosci (2011) 5: 89.
13.
Nishibayashi Y, Nambu A, Tachibana Y, and Itakura T.
Reply: Cortically evoked responses of human pallidal neuron.
Mov Disord (2011) 26(14): 2583-2584.

12.
Nishibayashi H, Ogura M, Kakishita K, Tanaka S, Nambu A, Tachibana Y, Kita H, and Itakura T.
Cortically evoked responses of human pallidal neurons recorded during stereotactic neurosurgery.
Mov Disord (2011) 26(3): 469-476.

11.
Tachibana Y, Kita H, Chiken S, Takada M, and Nambu A.
Motor cortical control of internal pallidal activity through glutamatergic and GABAergic inputs in awake monkeys.
Eur J Neurosci (2008) 27(1): 238-253.

10.
Kita H, Chiken S, Tachibana Y, and Nambu A.
Serotonin modulates pallidal neuronal activity in the awake monkey.
J Neurosci (2007) 27(1): 75-83.

9.
Kita H, Chiken S, Tachibana Y, and Nambu A.
Origins of GABAA and GABAB receptor-mediated responses of globus pallidus induced after stimulation of the putamen in the monkey.
J Neurosci (2006) 26(24): 6554-6562.

8.
Kaneda K*, Tachibana Y* , Imanishi M, Kita H, Shigemoto R, Nambu A, and Takada M. (* equally contributed)
Down-regulation of metabotropic glutamate receptor 1 in globus pallidus and substantia nigra of parkinsonian monkeys.
Eur J Neurosci (2005) 22(12): 3241-3254.

7.
Kita H, Tachibana Y, Nambu A, and Chiken S.
Balance of monosynaptic excitatory and disynaptic inhibitory responses of the globus pallidus induced after stimulation of the subthalamic nucleus in the monkey.
J Neurosci (2005) 25(38): 8611-8619.

6.
Masuda Y, Kim SK, Kato T, Iida S, Yoshida A, Tachibana Y, and Morimoto T.
Different corticostriatal projections from two parts of the cortical masticatory area in the rabbit.
Exp Brain Res (2005) 161(3): 397-404.

5.
Takada M, Nambu A, Hatanaka N, Tachibana Y, Miyachi S, Taira M, and Inase M.
Organization of prefrontal outflow toward frontal motor-related areas in macaque monkeys.
Eur J Neurosci (2004) 19(12): 3328-3342.

4.
Kita H, Nambu A, Kaneda K, Tachibana Y, and Takada M.
Role of ionotropic glutamatergic and GABAergic inputs on the firing activity of neurons in the external pallidum in awake monkeys.
J Neurophysiol (2004) 92(5): 3069-3084.

3.
Tachibana Y, Nambu A, Hatanaka N, Miyachi S, and Takada M.
Input-output organization of the rostral part of the dorsal premotor cortex, with special reference to its corticostriatal projection.
Neurosci Res (2004) 48(1): 45-57.

2.
Masuda Y, Tachibana Y, Inoue T, Iwata K, and Morimoto T.
Influence of oro-facial sensory input on the output of the cortical masticatory area in the anesthetized rabbit.
Exp Brain Res (2002) 146(4): 501-510.

1.
Iwata K, Imai T, Tsuboi Y, Tashiro A, Ogawa A, Morimoto T, Masuda Y, Tachibana Y, and Hu J.
Alteration of medullary dorsal horn neuronal activity following inferior alveolar nerve transection in rats.
J Neurophysiol (2001) 86(6): 2868-2877.

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