業績 Achievement

学会発表~国際発表(シンポジウム・一般演題)

2019

newKido Y
Regulation of pancreatic β cell mass from the interacion of gene-environmental factors
International Congress of Diabetes and Metabolism

newAsahara S, Kido Y
Early administration od dapagliflozin preserves pancreatic beta cell mass through an epigenetic modification in a mouse model of type2 diabetes
International Congress of Diabetes and Metabolism

newKudo M, Kanno A, Asahara S, Kido Y
Identification of the regulatory mechanism of mTORC1 signaling activity in pancreatic β-cells in GCN2 knockout mice
79th American Diabetes Association

2017

    

Asahara S, Ohashi Y, Kido Y
P-0503 Effect of removal of glucotoxicity by SGLT2 inhibitor dapagliflozin on the gene expression in pancreatic beta cells 
International Diabetes Federation

Kido Y
Beta cell mass
International Diabetes Federation

Shimono N, Asahara S, Kido Y
Analysis of Pathogenic Mechanism by Susceptibility Genes of T2DM Using Human iPS Cells
77th Scientific Sessions of American Diabetes Association

Kido Y
Regulation of pancreatic beta cell mass from the interaction of geneenvironment factors
9th AASD Scientific Meeting

Asahara S
Regulation of pancreatic beta cell mass through type 2 diabetes susceptibility genes
AIBIS 2017

    

2016

Asahara S
Pancreatic β-cell failure in Asian patients with type2 diabetes:Two Culprits
3rd Annual Meeting of DDES

Matsuura Y, Matsuda T, Takai T, Inoue K, Suzuki E, Asahara S,  Koyanagi-Kimura M, Kanno A, Kido Y
The role of casein kinase 2 in ER stress associated pancreatic β cell failure 
8th AASD Scientific Meeting

2015

Sugiura Y, Asahara S, Kawada Y, Ihara Y, Hara M, Kanno A, Kimura-Koyanagi M, Matsuda T, Seino S, Ogawa W, Kido Y
Histone deacetylase regulates insulin signaling via two pathways in pancreatic β cells 
7th AASD Scientific Meeting

Masuda K, Kanno A, Yoshitomi R, Asahara S, Matsuda T, Kimura M, Shibutani Y, Yokoi N, Kasuga M, Seino S, Kido Y
GCN2, a type 2 diabetes mellitus susceptibility gene, is associated with the regulation of pancreatic β-cell mass 
51st EASD Annual Meeting

Kanno A, Masuda K, Asahara S, Kimura M, Matsuda T, Kasuga M, Ogawa W, Seino S, Kido Y
GCN2, a Type 2 Diabetes Mellitus Susceptibility Gene, Is Associated with the Regulation of Pancreatic β-Cell Mass
75th Scientific Session of American Diabetes Association

Asahara S, Ihara Y, Inoue H, Teruyama K, Hara M, Kimura M, Matsuda T, Seino S, kido Y
Reduction in Pancreatic β-Cell Mass Caused by Enhanced Expression of Cdkn1c via Interaction between C/EBPβ and Epigenetic Control
75th Scientific Session of American Diabetes Association

2014

Ihara Y, Asahara S, Inoue H, Teruyama K, Matsuda T, Seino S, Kido Y
Reduction in pancreatic β-cell mass caused by enhanced expression of Cdkn1c via interaction between C/EBPβ and epigenetic control 
50th EASD Annual Meeting

Mieda Y, Takahashi H, Matsuda T, Takahashi H, Asahara S, Terashi E, Kanno A, Koyanagi M, Seino S, Kido Y
Cross-interaction between C/EBPβ and AMPK determines the pancreatic β-cell mass
50th EASD Annual Meeting

2013

Inoue H, Asahara S, Etoh H, Teruyama K, Ihara Y, Matsuda T, Koyanagi-Kimura M, Kanno A, Nagashima K, Nishimura W, Yasuda K, Inagaki N, Seino S, Kasuga M, Kido Y
Paternal allelic mutation at the Kcnq1 locus reduces pancreatic beta cell mass via epigenetic modification of Cdkn1c
49th EASD Annual Meeting

Takahashi H, Matsuda T, Mieda Y, Asahara S, Terashi E, Kanno A, Koyanagi M, Bartolome A, Seino S, Kido Y
Modulation of C/EBP beta expression via AMPK regulates pancreatic beta cell mass
49th EASD Annual Meeting

Asahara S, Etoh H, Inoue H, Teruyama K, Shibutani Y, Ihara Y, Bartolome A, Hashimoto N, Matsuda T, Koyanagi-Kimura M, Kanno A, Nagashima K, Nishimura W, Yasuda K, Inagaki N, Seino S, Kasuga M, Kido Y
Paternal allelic mutation at the Kcnq1 locus reduces pancreatic β-cell mass via epigenetic modification of Cdkn1c
The Scientific Program Committee of ICDM2013 and 5th AASD Scientific Meeting

Matsuda T, Takahashi H, Mieda Y, Kawamoto T, Terashi E, Kanno A, Kimura-Koyanagi M, Asahara S, Kido Y
Modulation of C/EBPβ expression via AMPK regulates pancreatic β-cell mass
The Scientific Program Committee of ICDM2013 and 5th AASD Scientific Meeting

Matsuda T, Takahashi H, Mieda Y, Asahara S, Kanno A, Koyanagi M, Seino S, Kido Y
Modulation of C/EBPβ expression via AMPK regulates pancreatic β-cell mass.
Beta Cell Workshop 2013 Kyoto

Kanno A, Yoshitomi R, Asahara S, Matsuda T, Koyanagi M, Shibutani Y, Yokoi N, Kasuga M, Seino S, Kido Y
GCN2, a type 2 diabetes mellitus susceptibility gene, is associated with the regulation of pancreatic β-cell mass.
Beta Cell Workshop 2013 Kyoto

Asahara S, Etoh H, Inoue H, Teruyama K, Shibutani Y, Ihara Y, Bartolome A, Hashimoto N, Matsuda T, Koyanagi-Kimura M, Kanno A, Nagashima K, Nishimura W, Yasuda K, Inagaki N, Seino S, Kasuga M, Kido Y
Paternal allelic mutation at the Kcnq1 locus reduces pancreatic β-cell mass via epigenetic modification of Cdkn1c. 
Beta Cell Workshop 2013 Kyoto

2012

Asahara S, Teruyama K, Etoh H, Inoue H, Ihara Y, Kawada Y, Matsuda T, Yasuda K, Kasuga M, Seino S, Kido Y
Reduction in pancreatic beta-cell mass by enhanced expression of Cdkn1c as a result of interaction between C/EBPbeta and epigenetic control
9th IDF/4th AASD

Matsuda T, Takahashi H, Mieda Y, Asahara S, Kannno A, Koyanagi M, Seino S, Kido Y
Protective effect of DPP-4 inhibitor Vildagliptin on pancreatic beta-cells in beta-cell specific C/EBPbeta transgenic mice.
9th IDF/4th AASD

Bartolome A, Kimura-Koyanagi M, Shimizu S, Kanno A, Guillen C, Benito M, Asahara S, Kido Y
Pancreatic beta cell failure mediated by mTORC1 hyperactivity and autophagic impairment.
48th EASD Annual Meeting

Teruyama K, Asahara S, Inoue H, Etoh H, Matsuda T, Seino S, Kido Y
Reduction in pancreatic beta cell mass caused by enhanced expression of Cdkn1c as a result of interaction between C/EBPβ and epigenetic control.
48th EASD Annual Meeting

Matsuda T
Protective effect of DPP-4 inhibitor vildagliptin (incretin) on pancreatic β-cells in diabetic β-cell specific C/EBPβ transgenic mice.
ⅩⅢ SERVIER-IGIS Symposium

Matsuda T
Regulation of Pancreatic Beta Cell Mass through ER stress.
2012 Asia-Pacific Diabetes and Obesity Study Group

2011

Kido Y
Regulation of beta-cell proliferation by mTOR signaling.
Programming Beta Cell Development, Impairment and Regeneration

Kimura-Koyanagi M
Ablation of TSC2 enhances insulin secretion by increasing the number of mitochondria.
Strategic Danish-Japanese Cooperative Program on Molecular Diabetology

Kido Y
Regulation of beta-cell proliferation by mTOR signaling.
Strategic Danish-Japanese Cooperative program on Molecular Diabetology

Fuchita M, Koyanagi M, Asahara S, Inoue T, Yoshida Y, Kasuga M, Seino S, Kido Y.
Effect of intrauterine undernutrition during late gestation on pancreatic beta cell mass.
47th EASD Annual Meeting

Shimizu S, Hosooka T, Matsuda T, Asahara S, Seino S, Kido Y.
Effect of DPP-4 inhibitor vildagliptin on pancreatic beta cell failure in beta cell-specific C/EBPβ transgenic mice.
47th EASD Annual Meeting

Asahara S
Rac1 Regulates Glucose-stimulated Insulin Secretion via Modulation of F-actin.
Kick-off Workshop Strategic Japanese-Danish Cooperative program on Molecular Diabetology

Kido Y
Regulation of pancreatic beta cell mass through ER stress.
Kick-off Workshop
Strategic Japanese-Danish Cooperative program on Molecular Diabetology

2010

Kido Y
Regulation of beta-cell size/mass.
Danish-Japanese Joint Workshop “Molecular Diabetology”

Koyanagi M, Kido Y, Asahara S, Shigeyama Y, Matsuda T, Shibutani Y, Fuchita M, Noda T, Seino S, Kasuga M.
Ablation of TSC2 enhances mitochondrial function via activation of mTORC1 in β cells.
70th Scientific Session of American Diabetes Association

Kido Y
TSC2, mTorC and Beta Cell Function
70th Scientific Session of American Diabetes Association

Kido Y
Ablation of C/EBPβ alleviates ER stress and pancreatic β cell failure through the GRP78 chaperone in mice.
Asian Islet Biology & Incretin Symposium (AIBIS) 2010

Kido Y
Ablation of C/EBPβ alleviates ER stress and pancreatic β cell failure through the GRP78 chaperone in mice.
5th Korea-Japan Islet Biology Club Meeting

2008

Asahara S, Kido Y, Shigeyama Y, Matsuda T, Takeda A, Inoue T, Shibutani Y, Koyanagi M, Uchida T, Kasuga M. 
Rac1 regulates glucose-induced insulin secretion through modulation of cytoskeletal organization in beta cells.
68th Scientific Session of American Diabetes Association

Kido Y
Biphasic response of pancreatic β cell mass to ablation of TSC2 in mice.
The 9th Symposium on Molecular Diabetology in Asia

Matsuda T, Kido Y, Asahara S, Shigeyama Y, Takeda A, Inoue T, Shibutani Y, Koyanagi M, Uchida T, Kasuga M.
Accumulation of C/EBPβ induces pancreatic β cell failure by suppressing the induction of GRP78 in the endoplasmic reticulum.
The 9th Symposium on Molecular Diabetology in Asia

2007

Matsuda T, Kido Y, Hashimoto N, Asahara S, Shigeyama Y, Takeda A, Inoue T, Shibutani Y, Uchida T, Kasuga M.
Accumulation of C/EBPβ induces pancreatic β cell failure by reducing the endoplasmic reticulum function.
67th Scientific Session of American Diabetes Association

Sigeyama Y, Kido Y, Hashimoto N, Asahara S, Matsuda T, Takeda A, Inoue T, Shibutani Y, Uchida T, Noda T, Kasuga M.
Role of TSC2 in the regulation of pancreatic β cell mass.
67th Scientific Session of American Diabetes Association

2003

Hashimoto N, Kido Y, Tsuchihashi D, Uchida T, Ohno S, Noda T, Kasuga M.
Defective glucose-induced insulin secretion in pancreatic β cell specific PKCλ knockout mice.
63th Scientific Session of American Diabetes Association

2000

Kido Y, Nakae J, Xuan S, Efstratiadis A, Accili D.
Beta cell development in mice lacking insulin and type 1 IGF receptors.
60th Scientific Session of American Diabetes Association