研究業績 | 微生物資源化学研究室

Takenaka S, Nakabayashi R, Ogawa C, Kimura Y, Yokota S, Doi M. Characterization of surfaceAspergilluscommunity involved in traditional fermentation and ripening of katsuobushi. Int J Food Microbiol. 327:108654 (2020).doi:10.1016/j.ijfoodmicro.2020.108654
Takenaka S, Ogawa C, Uemura M, Umeki T, Kimura Y, Yokota S, Doi M. Identification and characterization of extracellular enzymes secreted byAspergillusspp. involved in lipolysis and lipid-antioxidation during katsuobushi fermentation and ripening. Int J Food Microbiol. 353:109299 (2021).doi:10.1016/j.ijfoodmicro.2021.109299
Takenaka S, Toyoshima R, Umeki T, Kimura Y, Tanaka S, Matsumoto J, Doi M. Comparative analysis of lipolytic enzymes involved in the surface fermentation of dried katsuobushi by xerophilic molds. J Sci Food Agric. 105:3495-3503 (2025).doi:10.1002/jsfa.14170
Takenaka S, Lim L, Fukami T, Yokota S, Doi M. Isolation and characterization of an aspartic protease able to hydrolyze and decolorize heme proteins fromAspergillus glaucus. J Sci Food Agric. 99:2042-2047 (2019).doi:10.1002/jsfa.9339
Takenaka S, Umeda M, Senba H, Koyama D, Tanaka K, Yoshida K, Doi M. Heterologous expression and characterisation of theAspergillusaspartic protease involved in the hydrolysis and decolorisation of red-pigmented proteins. J Sci Food Agric. 97:95-101 (2017).doi:10.1002/jsfa.7688

Nishikawa A, Senba H, Kimura Y, Yokota S, Doi M, Takenaka S. Isolation and characterization of a salt-tolerant γ-glutamyl transpeptidase from xerophilicAspergillus sydowii. 3 Biotech. 12:253 (2022).doi:10.1007/s13205-022-03259-3
Senba H, Nishikawa A, Kimura Y, Tanaka S, Matsumoto J, Doi M, Takenaka S. Improvement in salt-tolerance ofAspergillus oryzaeγ-glutamyl transpeptidase via protein chimerization withAspergillus sydowii homolog. Enzyme Microb Technol. 167:110240 (2023).doi:10.1016/j.enzmictec.2023.110240
Senba H, Saito D, Kimura Y, Tanaka S, Doi M, Takenaka S. Heterologous expression and characterization of salt-tolerant β-glucosidase from xerophilicAspergillus chevalierifor hydrolysis of marine biomass. Arch Microbiol. 205:310 (2023). doi:10.1007/s00203-023-03648-z
Takenaka S, Takada A, Kimura Y, Watanabe M, Kuntiya A. Improvement of the halotolerance of aBacillusserine protease by protein surface engineering. J Basic Microbiol. 62:174-184 (2022).doi:10.1002/jobm.202100335
Lim L, Senba H, Kimura Y, Yokota S, Doi M, Yoshida KI, Takenaka S. Influences of N-linked glycosylation on the biochemical properties of aspartic protease fromAspergillus glaucusMA0196. Process Biochem. 79:74-80 (2019).doi:10.1016/j.procbio.2018.12.017
Takenaka S, Oribe Y, Matsumoto J, Doi M. Salt-tolerant endopeptidases from xerophilicAspergillus sydowiifor potentialapplications in meat processing. J Sci Food Agric. (2025). doi:10.1002/jsfa.70741

Takenaka S, Kato M, Oribe Y, Kimura Y, Tanaka S, Matsumoto J, Doi M. Exploring the potential of katsuobushi grounds as a source of bioactive peptides through fermentation withAspergillus sydowii. Process Biochem. 130:534-544 (2023).doi:10.1016/j.procbio.2023.05.017
Takenaka S, Yokoyama M, Kimura Y, Yamashita Y, Ashida H. Characterization of an organic-solvent-stable elastase fromPseudomonas indicaand its potential use in eggshell membrane hydrolysis. Process Biochem. 85:156-163 (2019).doi:10.1016/j.procbio.2019.06.021
Itatani H, Yamaki A, Konishi K, Okamoto H, Okumura N, Shigematsu N, Misumi S, Takenaka S. Fermented royal jelly enriched with 10-hydroxydecanoic acid and its potential for enhancing mucosal immunity. Food Sci Nutr. 13:e70041 (2025).doi:10.1002/fsn3.70041
Yakul K, Takenaka S, Peterbauer C, Haltrich D, Techapun C, Seesuriyachan P, Leksawasdi N, Chaiyaso T. Functional modification of thermostable alkaline protease fromBacillus haloduransSE5 for efficient production of antioxidative and ACE-inhibitory peptides from sericin. Biocatal Agric Biotechnol. 54:102943 (2023).doi:10.1016/j.bcab.2023.102943
Yakul K, Kaewsalud T, Techapun C, Seesuriyachan P, Jantanasakulwong K, Watanabe M, Takenaka S, Chaiyaso T. Enzymatic valorization process of yellow cocoon waste for production of antioxidative sericin and fibroin film. J Chem Technol Biotechnol. 96:953-962 (2021).doi:10.1002/jctb.6604